Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455202 | 0.84 | PPARA (0.55) | PPARAPPARDCHRM4GAASMN1; SMN2 | |
| SCHEMBL3454459 | 0.77 | SCD (0.55) | PPARAPPARDCHRM4SMN1; SMN2LMNA | |
| SCHEMBL3454348 | 0.77 | SCD (0.55) | SCD | |
| SCHEMBL3455026 | 0.77 | PPARA (0.55) | PPARAPPARDCHRM4GAASMN1; SMN2 | |
| SCHEMBL3454860 | 0.76 | MAOB (0.52) | LMNAALDH1A1THRBKMT2AMEN1 | |
| SCHEMBL3468898 | 0.76 | PPARA (0.52) | PPARAPPARDCHRM4SMN1; SMN2LMNA | |
| SCHEMBL3575995 | 0.76 | CHRM4 (0.61) | PPARAPPARDCHRM4GAASMN1; SMN2 | |
| SCHEMBL3455092 | 0.76 | PPARD (0.56) | PPARAPPARDCHRM4GAASMN1; SMN2 | |
| SCHEMBL3454756 | 0.75 | LMNA (0.45) | PPARAPPARDCHRM4GAASMN1; SMN2 | |
| SCHEMBL13541938 | 0.75 | PPARA (0.48) | PPARAPPARDCHRM4GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |