Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 4/20 | 0.35 |
| ▸ | DPP4 | P27487 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455010 | 0.88 | GRM6 (0.34) | DHPSDPP4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL1397100 | 0.87 | ALDH1A1 (0.42) | DHPSDPP4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL1397109 | 0.86 | ALDH1A1 (0.41) | DHPSDPP4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL16076589 | 0.81 | DHPS (0.38) | DHPSDPP4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL1918560 | 0.81 | DPP4 (0.37) | DHPSDPP4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL3781693 | 0.81 | DPP4 (0.30) | DPP4 | |
| SCHEMBL1397033 | 0.81 | DHPS (0.36) | DHPSDPP4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL27785284 | 0.81 | DHPS (0.36) | DHPSDPP4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL1397102 | 0.81 | ALDH1A1 (0.37) | DHPSKDM4EALDH1A1HSD17B10KMO | |
| SCHEMBL1918405 | 0.80 | ALDH1A1 (0.38) | DHPSDPP4KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181098-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2010-05-05 | — | — | EP | disclosed |
| WO-2009029735-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-03-05 | — | — | WO | disclosed |