Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | DHPS | P49366 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455271 | 0.88 | DHPS (0.35) | HSD17B10KDM4EDPP4ALDH1A1DHPS | |
| SCHEMBL1397124 | 0.88 | GRM6 (0.37) | GRM6TP53RAB9AHSD17B10KDM4E | |
| SCHEMBL1397097 | 0.83 | GRM6 (0.34) | GRM6TP53RAB9AHSD17B10KDM4E | |
| SCHEMBL1397018 | 0.83 | ALDH1A1 (0.36) | GRM6TP53RAB9AHSD17B10KDM4E | |
| SCHEMBL679235 | 0.82 | GRM6 (0.37) | GRM6TP53RAB9AHSD17B10KDM4E | |
| SCHEMBL1918560 | 0.80 | DPP4 (0.37) | HSD17B10KDM4EDPP4ALDH1A1SMN1; SMN2 | |
| SCHEMBL3455141 | 0.80 | HTT (0.39) | TP53RAB9AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL1397168 | 0.79 | PRKCZ (0.41) | RAB9AHSD17B10KDM4EDPP4MAPT | |
| SCHEMBL3781927 | 0.79 | DPP4 (0.33) | KDM4EDPP4ALDH1A1SMN1; SMN2 | |
| SCHEMBL30151443 | 0.78 | KDM4E (0.39) | HSD17B10KDM4EALDH1A1SMN1; SMN2DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181098-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2010-05-05 | — | — | EP | disclosed |
| WO-2009029735-A1 | 2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-03-05 | — | — | WO | disclosed |