Alacepril

Alacepril

SCHEMBL34559

CC(=O)SC[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACE P12821 9/20 0.55
SLC6A2 P23975 1/20 0.54
ACE2 Q9BYF1 4/20 0.54
CMA1 P23946 2/20 0.53
OPRM1 P35372 1/20 0.51
DPP3 Q9NY33 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alacepril SCHEMBL11460465 1.00 ACE (0.55) ACESLC6A2ACE2CMA1OPRM1
Alacepril SCHEMBL5058556 1.00 ACE (0.55) ACESLC6A2ACE2CMA1OPRM1
Alacepril SCHEMBL20126832 1.00 ACE (0.55) ACESLC6A2ACE2CMA1OPRM1
Alacepril SCHEMBL683027 1.00 ACE (0.55) ACESLC6A2ACE2CMA1OPRM1
Alacepril SCHEMBL3204613 1.00 ACE (0.55) ACESLC6A2ACE2CMA1OPRM1
Alacepril SCHEMBL28035498 1.00 ACE (0.55) ACESLC6A2ACE2CMA1OPRM1
Alacepril SCHEMBL677447 1.00 ACE (0.55) ACESLC6A2ACE2CMA1OPRM1
Alacepril SCHEMBL11458085 0.95 ACE (0.51) ACESLC6A2ACE2CMA1OPRM1
SCHEMBL11282561 0.93 SLC6A2 (0.56) ACESLC6A2CMA1OPRM1
SCHEMBL683119 0.93 SLC6A2 (0.56) ACESLC6A2CMA1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8887 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087680-A1 TREATMENT FOR CARDIOVASCULAR DISEASE SAPREME TECHNOLOGIES B.V. (NL) 2026-04-30 WO claimed
EP-4595974-A2 THERAPEUTIC COMBINATIONS OF TDFRPS AND ADDITIONAL AGENTS AND METHODS OF USE Carlson, William D. (US) 2025-08-06 EP claimed
US-20250082608-A1 TREATMENT AND PREVENTION OF GLOMERULAR DISEASE SINGAPORE HEALTH SERVICES PTE LTD. (SG) 2025-03-13 US claimed
US-20240374587-A1 MEDICINE FOR PREVENTION AND TREATMENT OF DISEASES LINKED TO ANTI-OBESITY ACTIVITY SHIONOGI & CO., LTD. (JP) 2024-11-14 US claimed
EP-4448096-A1 TREATMENT AND PREVENTION OF GLOMERULAR DISEASE Singapore Health Services Pte. Ltd. (SG) 2024-10-23 EP claimed
WO-2024210922-A1 COMPOSITIONS FOR ANTIHYPERTENSIVE DRUGS INNOVATOR THERAPEUTICS, LLC. (US) 2024-10-10 WO claimed
EP-3083573-B1 INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL MERCK SHARP & DOHME LLC (US) 2024-08-07 EP claimed
EP-4400105-A1 MEDICINE FOR PREVENTION AND TREATMENT OF DISEASES LINKED TO ANTI-OBESITY ACTIVITY Shionogi & Co., Ltd (JP) 2024-07-17 EP claimed
US-20240123033-A1 THERAPEUTIC COMBINATIONS OF TDFRPs AND ADDITIONAL AGENTS AND METHODS OF USE FOR THE REVERSAL OF FIBROSIS Therapeutics By Design, LLC (US) 2024-04-18 US claimed
US-11931341-B2 Compositions and methods for the treatment and prevention of muscular dystrophy UNIVERSITY OF LOWA RESEARCH FOUNDATION (US) 2024-03-19 US claimed
EP-0391462-A1 Synergistic compositions containing ketanserin JANSSEN PHARMACEUTICA N.V. (BE) 1990-10-10 EP claimed
EP-0272177-B1 PHARMACEUTICAL COMPOSITION CONTAINING DILTIAZEM AND AN INHIBITOR OF THE ENZYME-TRANSFORMING ANGIOTENSIN SYNTHELABO (FR) 1990-07-04 EP claimed
EP-0363671-A2 Use of ACE inhibitors against the formation of neo-intima after vascular infliction F. HOFFMANN-LA ROCHE AG (CH) 1990-04-18 EP claimed
EP-0351017-A2 Pharmaceutical composition useful for the treatment of cardiovascular diseases ZAMBON GROUP S.p.A. (IT) 1990-01-17 EP claimed
EP-0320097-A1 Controlled absorption diltiazem formulations ELAN CORPORATION, Plc (IE) 1989-06-14 EP claimed
EP-0220107-A2 Use of angiotensin-converting enzyme inhibitors in macular degeneration MERCK & CO. INC. (US) 1987-04-29 EP claimed
US-4656188-A Ace inhibitors in macular degeneration MERCK & CO., INC. (US) 1987-04-07 US claimed
EP-0007477-B1 1-(3-MERCAPTO-2-METHYLPROPANOYL)PROLYL AMINO ACID DERIVATIVES AND SALTS THEREOF, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS Dainippon Pharmaceutical Co., Ltd. (JP) 1982-04-28 EP claimed
US-4248883-A ANTIHYPERTENSION AGENTS DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1981-02-03 US claimed
EP-0007477-A1 1-(3-Mercapto-2-methylpropanoyl)prolyl amino acid derivatives and salts thereof, processes for their preparation, and pharmaceutical compositions containing such compounds Dainippon Pharmaceutical Co., Ltd. (JP) 1980-02-06 EP claimed