Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.54 |
| ▸ | CMA1 | P23946 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alacepril SCHEMBL11460465 | 1.00 | ACE (0.55) | ACESLC6A2ACE2CMA1OPRM1 | |
| Alacepril SCHEMBL5058556 | 1.00 | ACE (0.55) | ACESLC6A2ACE2CMA1OPRM1 | |
| Alacepril SCHEMBL20126832 | 1.00 | ACE (0.55) | ACESLC6A2ACE2CMA1OPRM1 | |
| Alacepril SCHEMBL34559 | 1.00 | ACE (0.55) | ACESLC6A2ACE2CMA1OPRM1 | |
| Alacepril SCHEMBL3204613 | 1.00 | ACE (0.55) | ACESLC6A2ACE2CMA1OPRM1 | |
| Alacepril SCHEMBL28035498 | 1.00 | ACE (0.55) | ACESLC6A2ACE2CMA1OPRM1 | |
| Alacepril SCHEMBL677447 | 1.00 | ACE (0.55) | ACESLC6A2ACE2CMA1OPRM1 | |
| Alacepril SCHEMBL11458085 | 0.95 | ACE (0.51) | ACESLC6A2ACE2CMA1OPRM1 | |
| SCHEMBL11282561 | 0.93 | SLC6A2 (0.56) | ACESLC6A2CMA1OPRM1 | |
| SCHEMBL683119 | 0.93 | SLC6A2 (0.56) | ACESLC6A2CMA1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110046090-A1 | MODULATION OF NEUROGENESIS WITH GABA AGENTS AND GABA ANALOGS | BRAINCELLS INC. (US) | 2011-02-24 | — | — | US | disclosed |
| US-20110046090-A1 | MODULATION OF NEUROGENESIS WITH GABA AGENTS AND GABA ANALOGS | BRAINCELLS INC. (US) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046090-A1 | MODULATION OF NEUROGENESIS WITH GABA AGENTS AND GABA ANALOGS | GAP43, GABRB1, GABRB3 | ACE 4514/4885SLC6A2 280/4885ACE2 4392/4885 |
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | ACE 6/4885SLC6A2 376/4885ACE2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.