SCHEMBL3456730

SCHEMBL3456730

NS(=O)(=O)N1C=CN(S(=O)(=O)c2c[nH]c3ccccc23)N1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
GAA P10253 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP3A4 P08684 2/20 0.40
MPO P05164 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2A6 P11509 1/20 0.40
NFKB1 P19838 1/20 0.40
HTR1D P28221 1/20 0.40
HTR1B P28222 1/20 0.40
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
HTR7 P34969 1/20 0.40
CTSK P43235 1/20 0.40
HTR6 P50406 1/20 0.40
CYP2A13 Q16696 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
PMP22 Q01453 1/20 0.39
BCHE P06276 1/20 0.38
SLC22A6 Q4U2R8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32896 0.74 CYP3A4 (0.48) ALDH1A1GAACYP2D6CYP3A4MPO
SCHEMBL27148809 0.70 SLC22A6 (0.50) ALDH1A1GAACYP3A4CYP2A6HTR6
SCHEMBL28939777 0.69 SLC22A6 (0.49) ALDH1A1GAACYP3A4CYP2A6SLC22A6
SCHEMBL29557960 0.68 PBRM1 (0.52) ALDH1A1GAACYP3A4CYP2A6SLC22A6
SCHEMBL517162 0.68 SLC22A6 (0.47) ALDH1A1GAACYP3A4CYP2A6SLC22A6
SCHEMBL15415994 0.68 PBRM1 (0.52) ALDH1A1GAACYP3A4CYP2A6SLC22A6
SCHEMBL329511 0.68 SLC22A6 (0.56) ALDH1A1GAACYP3A4CYP2A6SLC22A6
SCHEMBL5513343 0.68 SLC22A6 (0.47) ALDH1A1GAACYP3A4CYP2A6SLC22A6
SCHEMBL3456728 0.67 ALDH1A1 (0.38) ALDH1A1GAACYP2D6CYP3A4MPO
SCHEMBL30897299 0.67 POLB (0.57) ALDH1A1GAAHTR6MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2255627-A2 Fungicidal mixtures BASF SE (DE) 2010-12-01 EP disclosed
EP-2255630-A2 Fungicidal mixtures BASF SE (DE) 2010-12-01 EP disclosed
EP-2255629-A2 Fungicidal mixtures BASF SE (DE) 2010-12-01 EP disclosed
EP-2255628-A2 Fungicidal mixtures BASF SE (DE) 2010-12-01 EP disclosed