SCHEMBL3456728

SCHEMBL3456728

NS(=O)(=O)n1cc(S(=O)(=O)c2c[nH]c3ccccc23)nn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
GAA P10253 1/20 0.38
AKT1 P31749 1/20 0.38
PIK3CA P42336 1/20 0.38
HTR6 P50406 2/20 0.37
MAPT P10636 3/20 0.36
SLC22A6 Q4U2R8 1/20 0.35
MET P08581 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
TP53 P04637 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
CYP3A4 P08684 2/20 0.35
AHR P35869 1/20 0.35
GPR84 Q9NQS5 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MPO P05164 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2A6 P11509 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27148809 0.75 SLC22A6 (0.50) ALDH1A1GAAHTR6MAPTSLC22A6
SCHEMBL32896 0.72 CYP3A4 (0.48) ALDH1A1GAAHTR6MAPTSLC22A6
SCHEMBL4448917 0.70 TP53 (0.40) ALDH1A1GAAHTR6MAPTSLC22A6
SCHEMBL2037678 0.70 MET (0.59) ALDH1A1GAAHTR6MAPTMET
SCHEMBL4449411 0.69 AKR1B1 (0.62)
SCHEMBL28939777 0.67 SLC22A6 (0.49) ALDH1A1GAAMAPTSLC22A6MEN1
SCHEMBL3456730 0.67 ALDH1A1 (0.40) ALDH1A1GAAHTR6MAPTSLC22A6
SCHEMBL15415994 0.66 PBRM1 (0.52) ALDH1A1GAAMAPTSLC22A6MEN1
SCHEMBL5513343 0.66 SLC22A6 (0.47) ALDH1A1GAAMAPTSLC22A6MEN1
SCHEMBL517162 0.66 SLC22A6 (0.47) ALDH1A1GAAMAPTSLC22A6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2255627-A2 Fungicidal mixtures BASF SE (DE) 2010-12-01 EP disclosed
EP-2255630-A2 Fungicidal mixtures BASF SE (DE) 2010-12-01 EP disclosed
EP-2255629-A2 Fungicidal mixtures BASF SE (DE) 2010-12-01 EP disclosed
EP-2255628-A2 Fungicidal mixtures BASF SE (DE) 2010-12-01 EP disclosed