Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13844254 | 0.96 | LCK (0.52) | TSHRLCKDRD3DNM1ZDHHC20 | |
| SCHEMBL151280 | 0.90 | TSHR (0.57) | TSHRLCKDRD3ALDH1A1TDP1 | |
| SCHEMBL8035581 | 0.90 | LCK (0.52) | TSHRLCKALDH1A1TDP1MAPT | |
| SCHEMBL17451526 | 0.90 | LCK (0.52) | TSHRLCKALDH1A1TDP1MAPT | |
| SCHEMBL11141675 | 0.88 | TSHR (0.56) | TSHRLCKDNM1ZDHHC20ZDHHC2 | |
| SCHEMBL23389008 | 0.87 | LCK (0.54) | TSHRLCKALDH1A1TDP1MAPT | |
| SCHEMBL11137053 | 0.84 | LCK (0.54) | TSHRLCKDRD3DNM1ZDHHC20 | |
| SCHEMBL3145967 | 0.84 | LCK (0.54) | TSHRLCKDRD3DNM1ZDHHC20 | |
| SCHEMBL4457197 | 0.84 | LCK (0.54) | TSHRLCKDRD3DNM1ZDHHC20 | |
| SCHEMBL6153439 | 0.84 | LCK (0.54) | TSHRLCKDRD3DNM1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900724-B1 | Process for the preparation of tertiary amines from primary amines and nitriles | INVISTA TECHNOLOGIES SRL (CH) | 2014-12-17 | — | — | EP | disclosed |
| EP-2264006-A1 | Process for the preparation of tertiary amines from primary amines and nitriles | Invista Technologies S.à.r.l. (CH) | 2010-12-22 | — | — | EP | disclosed |
| EP-1444193-B1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINES FROM PRIMARY AMINES AND NITRILES | INVISTA TECH SARL (CH) | 2008-10-08 | — | — | EP | disclosed |
| EP-1900724-A2 | Process for the preparation of tertiary amines from primary amines and nitriles | Invista Technologies S.a.r.l. (CH) | 2008-03-19 | — | — | EP | disclosed |
| EP-1444193-A4 | PROCESS FOR THE PREPARATION OF TERTIARY AMINES FROM PRIMARY AMINES AND NITRILES | DU PONT (US) | 2006-02-15 | — | — | EP | disclosed |
| CN-1547602-A | Acid-dyeable polymer compositions | ��Ļ���Ű˾ | 2004-11-17 | — | — | CN | disclosed |
| EP-1444193-A2 | PROCESS FOR THE PREPARATION OF TERTIARY AMINES FROM PRIMARY AMINES AND NITRILES | E. I. du Pont de Nemours and Company (US) | 2004-08-11 | — | — | EP | disclosed |
| EP-1419196-A1 | ACID DYEABLE POLYMER COMPOSITIONS | INVISTA Technologies S.à.r.l. (US) | 2004-05-19 | — | — | EP | disclosed |
| US-6723799-B2 | BLENDS OF POLYESTER WITH NYLON; FIBERS, FABRICS AND FILMS | E I. DU PONT DE NEMOURS AND COMPANY | 2004-04-20 | — | — | US | disclosed |
| US-6600075-B1 | Preparing tertiary amine compounds from primary amines and nitrites in the presence of hydrogen gas and a metal catalyst, or metal-containing catalyst composition, at a temperature from about 50 degrees C. to about 200 degrees C. | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-07-29 | — | — | US | disclosed |
| US-20030135052-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINES FROM PRIMARY AMINES AND NITRILES | INVISTA NORTH AMERICA S.A.R.L. | 2003-07-17 | — | — | US | disclosed |
| WO-2003042134-A2 | PROCESS FOR THE PREPARATION OF TERTIARY AMINES FROM PRIMARY AMINES AND NITRILES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-05-22 | — | — | WO | disclosed |
| US-20030083441-A1 | Acid dyeable polymer compositions | INVISTA NORTH AMERICA S.A.R.L. | 2003-05-01 | — | — | US | disclosed |
| WO-2003018689-A1 | ACID DYEABLE POLYMER COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135052-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINES FROM PRIMARY AMINES AND NITRILES | NOS2, NOS1, PNMT | TSHR 3479/4885LCK 3484/4885DRD3 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.