SCHEMBL8035581

SCHEMBL8035581

N#CCCCCCN(CCCCCC#N)CCCCCC#N

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.52
TSHR P16473 3/20 0.41
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAPT P10636 1/20 0.36
HIF1A Q16665 2/20 0.33
EPAS1 Q99814 2/20 0.33
LOX P28300 1/20 0.32
LOXL3 P58215 1/20 0.32
LOXL2 Q9Y4K0 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17451526 1.00 LCK (0.52) LCKTSHRALDH1A1TDP1MAPT
SCHEMBL23389008 0.97 LCK (0.54) LCKTSHRALDH1A1TDP1MAPT
SCHEMBL3456784 0.90 TSHR (0.52) LCKTSHRALDH1A1TDP1MAPT
SCHEMBL714027 0.88 LCK (0.65) LCKTSHRALDH1A1TDP1LOX
SCHEMBL15591979 0.88 LCK (0.65) LCKTSHRALDH1A1TDP1LOX
SCHEMBL714217 0.88 LCK (0.65) LCKTSHRALDH1A1TDP1LOX
SCHEMBL15591987 0.88 LCK (0.65) LCKTSHRALDH1A1TDP1LOX
SCHEMBL15591981 0.88 LCK (0.65) LCKTSHRALDH1A1TDP1LOX
SCHEMBL17038665 0.88 LCK (0.65) LCKTSHRALDH1A1TDP1LOX
SCHEMBL8439311 0.88 LCK (0.72) LCKTSHRALDH1A1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333375-A1 CYANOCARBON COMPOSITIONS ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2025-10-30 US disclosed
US-12215070-B2 Cyanocarbon compositions ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2025-02-04 US disclosed
EP-4061795-A1 COMPOSITIONS COMPRISING TRISCYANOHEXANE Ascend Performance Materials Operations LLC (US) 2022-09-28 EP disclosed
CN-114555554-A Composition comprising hexanetricarbonitrile 奥升德功能材料运营有限公司 2022-05-27 CN disclosed
US-20210155579-A1 CYANOCARBON COMPOSITIONS ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2021-05-27 US disclosed
WO-2021102286-A1 COMPOSITIONS COMPRISING TRISCYANOHEXANE ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2021-05-27 WO disclosed
EP-0807120-B1 RUTHENIUM HYDROGENATION CATALYSTS DU PONT (US) 2000-04-26 EP disclosed
EP-0807098-B1 IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES DU PONT (US) 1998-09-09 EP disclosed
US-5741955-A TRANSITION METAL COMPLEX CATALYST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-04-21 US disclosed
EP-0807098-A1 IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-11-19 EP disclosed
EP-0807120-A1 RUTHENIUM HYDROGENATION CATALYSTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-11-19 EP disclosed
US-5689003-A CATALYTIC HYDROGENATION OF NITRILES TO FORM AMINES WITH COMPLEXES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-11-18 US disclosed
US-5554778-A IMINATION, REDUCTIVE HYDROLYSIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-09-10 US disclosed
WO-1996023803-A1 RUTHENIUM HYDROGENATION CATALYSTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-08-08 WO disclosed
WO-1996023753-A1 IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-08-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12215070-B2 Cyanocarbon compositions CYCS, CBR3, PCCA LCK 1949/4885TSHR 4133/4885ALDH1A1 3668/4885
US-20250333375-A1 CYANOCARBON COMPOSITIONS CYCS, CBR3, PCCA LCK 1949/4885TSHR 4133/4885ALDH1A1 3668/4885
US-20210155579-A1 CYANOCARBON COMPOSITIONS CYCS, CBR3, PCCA LCK 1949/4885TSHR 4133/4885ALDH1A1 3668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.