Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.67 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113589 | 0.93 | BCHE (0.69) | BCHEMTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL5120825 | 0.91 | BCHE (0.55) | BCHEMTNR1AMTNR1BRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL4949263 | 0.84 | BCHE (0.77) | BCHERAB9ANPC1PKMLMNA | |
| SCHEMBL5113660 | 0.84 | BCHE (0.57) | BCHEMTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL3457501 | 0.82 | HTT (0.65) | BCHERAB9ANPC1PKMLMNA | |
| SCHEMBL6136381 | 0.82 | BCHE (0.64) | BCHEMTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL3051565 | 0.81 | LMNA (0.74) | BCHERAB9ANPC1PKMLMNA | |
| SCHEMBL3458474 | 0.81 | KMT2A (0.70) | BCHERAB9ALMNAHTTKDM4E | |
| SCHEMBL14078228 | 0.81 | BCHE (0.62) | BCHEMTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL9416614 | 0.80 | LMNA (0.73) | BCHERAB9ANPC1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007080109-A1 | SUBSTITUDED BENZYLOXY-PHENYLMETHYLUREA DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-19 | — | — | WO | disclosed |