Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17430943 | 0.98 | TDP1 (0.34) | KDM4EMAPTALOX15SMN1; SMN2TDP1 | |
| SCHEMBL9199990 | 0.90 | KMT2A (0.37) | SMN1; SMN2TDP1HDAC1HDAC2HDAC6 | |
| SCHEMBL8412132 | 0.85 | ALOX15 (0.42) | KDM4EMAPTALOX15SMN1; SMN2TDP1 | |
| SCHEMBL6534869 | 0.81 | STING1 (0.33) | HDAC1HDAC2HDAC6HDAC3HDAC8 | |
| SCHEMBL18195629 | 0.80 | MEN1 (0.36) | HDAC1HDAC2HDAC6HDAC3HDAC8 | |
| SCHEMBL1758843 | 0.80 | ALOX15 (0.41) | KDM4EMAPTALOX15SMN1; SMN2TDP1 | |
| SCHEMBL3031948 | 0.80 | ALOX15 (0.41) | KDM4EMAPTALOX15SMN1; SMN2TDP1 | |
| SCHEMBL16267787 | 0.80 | TDP1 (0.33) | TDP1CA14EPHX2 | |
| SCHEMBL14576346 | 0.79 | MEN1 (0.34) | HDAC1HDAC2HDAC6HDAC3HDAC8 | |
| Hydrochloric Acid SCHEMBL6840669 | 0.79 | MEN1 (0.34) | HDAC1HDAC2HDAC6HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266954-A1 | Novel bifunctional chelating compounds containing hydroxamic acid residues | Draximage, Inc. (CA) | 2010-12-29 | — | — | EP | disclosed |
| US-7238339-B2 | Bifunctional chelating compounds containing hydroxamic acid residues | DRAXIS SPECIALTY PHARMACEUTICALS INC. (CA) | 2007-07-03 | — | — | US | disclosed |
| US-20040086460-A1 | Novel bifunctional chelating compounds containing hydroxamic acid residues | JUBILANT DRAXIMAGE INC. (CA) | 2004-05-06 | — | — | US | disclosed |
| US-6623721-B2 | Conjugates can be complexed to a radioisotope metallic element and used for diagnosing or treating receptor-positive tumors | DRAXIMAGE, INC. (CA) | 2003-09-23 | — | — | US | disclosed |
| US-20020076377-A1 | Novel bifunctional chelating compounds containing hydroxamic acid residues | JUBILANT DRAXIMAGE INC. (CA) | 2002-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020076377-A1 | Novel bifunctional chelating compounds containing hydroxamic acid residues | EPRS1, HAMP, PHPT1 | KDM4E 3311/4885MAPT 3867/4885ALOX15 4575/4885 |
| US-20040086460-A1 | Novel bifunctional chelating compounds containing hydroxamic acid residues | EPRS1, HAMP, PHPT1 | KDM4E 3311/4885MAPT 3867/4885ALOX15 4575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.