Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397405 | 0.95 | KDM4E (0.35) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL7177419 | 0.90 | THRB (0.39) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL2778925 | 0.86 | HDAC8 (0.34) | RAB9AMAPTNPC1SMN1; SMN2LMNA | |
| SCHEMBL20494988 | 0.85 | ALOX5 (0.30) | ALOX5 | |
| SCHEMBL373843 | 0.84 | NPC1 (0.35) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL29613654 | 0.84 | NPC1 (0.35) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL8400550 | 0.82 | NPC1 (0.38) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL23638712 | 0.81 | NPC1 (0.37) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL6379811 | 0.80 | THRB (0.47) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL8397404 | 0.80 | TDP1 (0.37) | RAB9AKDM4EMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180356561-A1 | GEL, GEL MANUFACTURING METHOD, LENS, CONTACT LENS SURFACE MODIFIER, POLYMERIZABLE COMPOSITION, AND POLYMER | JSR CORPORATION (JP) | 2018-12-13 | — | — | US | disclosed |