Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17274189 | 0.90 | ALDH1A1 (0.51) | ALDH1A1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL12468575 | 0.88 | ALDH1A1 (0.50) | ALDH1A1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL3464975 | 0.82 | MEN1 (0.44) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6451025 | 0.81 | ALDH1A1 (0.49) | KMT2AALDH1A1RAB9ALMNAPOLB | |
| SCHEMBL19846329 | 0.81 | ALDH1A1 (0.45) | ALDH1A1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL25737139 | 0.81 | ALDH1A1 (0.45) | ALDH1A1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL11204077 | 0.81 | LTA4H (0.47) | ALDH1A1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL6595731 | 0.81 | ALDH1A1 (0.45) | ALDH1A1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL28319542 | 0.81 | TAAR1 (0.50) | ALDH1A1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL14557453 | 0.81 | L3MBTL1 (0.55) | KMT2AMEN1ALDH1A1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065578-A1 | Substituted Pyridin-4-ylmethyl Sulfonamides | BASF SE (DE) | 2011-03-17 | — | — | US | disclosed |
| WO-2009141290-A9 | SUBSTITUTED PYRIDIN-4-YLMETHYL SULFONAMIDES | BASF SE (DE) | 2010-11-25 | — | — | WO | disclosed |
| WO-2009141290-A2 | SUBSTITUTED PYRIDIN-4-YLMETHYL SULFONAMIDES | BASF SE (DE) | 2009-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065578-A1 | Substituted Pyridin-4-ylmethyl Sulfonamides | NANS, PNPO, NQO2 | KMT2A 1082/4885MEN1 3162/4885ALDH1A1 1715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.