Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10364192 | 0.82 | MEN1 (0.47) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL3459447 | 0.82 | KMT2A (0.47) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL25280430 | 0.82 | DRD2 (0.45) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL749431 | 0.82 | KCNA3 (0.54) | DRD4DRD2DRD3 | |
| SCHEMBL9326275 | 0.81 | MMP1 (0.51) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL1345118 | 0.78 | MAOB (0.57) | DRD4DRD2DRD3KCNH2ALDH3A1 | |
| SCHEMBL9770319 | 0.75 | DRD4 (0.59) | DRD4DRD2DRD3KCNH2ALDH3A1 | |
| SCHEMBL9770302 | 0.75 | ALDH3A1 (0.62) | DRD4DRD2DRD3KCNH2ALDH3A1 | |
| SCHEMBL1777301 | 0.74 | DRD4 (0.48) | DRD4DRD2DRD3KCNH2L3MBTL1 | |
| SCHEMBL30514014 | 0.73 | HRH3 (0.61) | DRD4DRD2DRD3KCNH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102036560-A | Substituted pyridin-4-ylmethyl sulfonamides | BASF SE | 2011-04-27 | — | — | CN | disclosed |
| US-20110065578-A1 | Substituted Pyridin-4-ylmethyl Sulfonamides | BASF SE (DE) | 2011-03-17 | — | — | US | disclosed |
| WO-2009141290-A9 | SUBSTITUTED PYRIDIN-4-YLMETHYL SULFONAMIDES | BASF SE (DE) | 2010-11-25 | — | — | WO | disclosed |
| WO-2009141290-A2 | SUBSTITUTED PYRIDIN-4-YLMETHYL SULFONAMIDES | BASF SE (DE) | 2009-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065578-A1 | Substituted Pyridin-4-ylmethyl Sulfonamides | NANS, PNPO, NQO2 | MEN1 3162/4885KMT2A 1082/4885CA1 2058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.