Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27544629 | 0.83 | NPC1 (0.56) | MAPTRAB9ANPC1CA12CA9 | |
| SCHEMBL19403807 | 0.81 | CXCR1 (0.50) | CXCR1MAPTRAB9ANPC1CA12 | |
| SCHEMBL16549592 | 0.80 | RAB9A (0.54) | CXCR1MAPTRAB9ANPC1CA12 | |
| SCHEMBL189588 | 0.80 | NOTUM (0.60) | CXCR1MAPTRAB9ANPC1CA12 | |
| SCHEMBL2294299 | 0.80 | PTPN1 (0.47) | CXCR1MAPTRAB9ANPC1CA12 | |
| SCHEMBL1220104 | 0.76 | CA12 (0.52) | CXCR1MAPTRAB9ANPC1CA12 | |
| SCHEMBL26215511 | 0.76 | MEN1 (0.59) | CXCR1MAPTRAB9ANPC1CA12 | |
| SCHEMBL2920882 | 0.76 | NOTUM (0.60) | CXCR1MAPTRAB9ANPC1CA12 | |
| SCHEMBL28689579 | 0.76 | NPC1 (0.67) | CXCR1MAPTRAB9ANPC1CA12 | |
| SCHEMBL26215233 | 0.76 | RAB9A (0.49) | CXCR1MAPTRAB9ANPC1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1717231-B1 | SUBSTITUTED AZOLE COMPOUNDS AND THEREOF PREPARATION AND APPLICATION | SINOCHEM CORP (CN) | 2015-09-02 | — | — | EP | disclosed |
| US-7795179-B2 | Substituted azole compounds and its preparation and use thereof | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2010-09-14 | — | — | US | disclosed |
| US-20080108668-A1 | Substituted azole compounds and its preparation and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2008-05-08 | — | — | US | disclosed |
| EP-1717231-A1 | SUBSTITUTED AZOLE COMPOUNDS AND THEREOF PREPARATION AND APPLICATION | Shenyang Research Institute of Chemical Industry (CN) | 2006-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108668-A1 | Substituted azole compounds and its preparation and use thereof | DDT, CRY1, WAPL | CXCR1 3753/4885MAPT 335/4885RAB9A 1034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.