Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18855210 | 0.79 | TAS1R3 (0.48) | RAB9AKMT2AMEN1NPC1MAPK14 | |
| SCHEMBL9017627 | 0.77 | MAPK14 (0.55) | RAB9AKMT2AMEN1NPC1MAPK14 | |
| SCHEMBL7856701 | 0.76 | KMT2A (0.56) | RAB9AKMT2AMEN1NPC1MAPK14 | |
| SCHEMBL16664390 | 0.75 | DOT1L (0.46) | RAB9AKMT2AMEN1NPC1HPGD | |
| SCHEMBL8210765 | 0.72 | RAB9A (0.72) | RAB9AKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL3455501 | 0.72 | RAB9A (0.72) | RAB9AKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL7187483 | 0.71 | ALDH1A1 (0.68) | RAB9AKMT2AMEN1NPC1TAS1R3 | |
| SCHEMBL7845992 | 0.71 | MAPK14 (0.52) | RAB9AKMT2AMEN1NPC1MAPK14 | |
| SCHEMBL5021982 | 0.71 | ALDH1A1 (0.63) | RAB9AKMT2AMEN1NPC1P2RX7 | |
| SCHEMBL9884064 | 0.71 | P2RX7 (0.58) | RAB9AKMT2AMEN1NPC1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239012-A2 | Pharmaceutical use of substituted amides | High Point Pharmaceuticals, LLC (US) | 2010-10-13 | — | — | EP | disclosed |