Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22366757 | 0.97 | ALDH1A1 (0.42) | ALDH1A1RAPGEF4L3MBTL1HDAC4CYP3A4 | |
| Hydrochloric Acid SCHEMBL29399312 | 0.97 | ALDH1A1 (0.42) | ALDH1A1RAPGEF4L3MBTL1HDAC4CYP3A4 | |
| Hydrochloric Acid SCHEMBL22366756 | 0.95 | ALDH1A1 (0.41) | ALDH1A1RAPGEF4L3MBTL1HDAC4 | |
| SCHEMBL3670715 | 0.86 | CYP3A4 (0.43) | ALDH1A1L3MBTL1CYP3A4TSHRMAPK1 | |
| SCHEMBL67360 | 0.80 | RAPGEF4 (0.42) | ALDH1A1RAPGEF4HDAC4GAAHDAC1 | |
| SCHEMBL12950434 | 0.79 | KDM4E (0.45) | ALDH1A1CYP3A4TSHRMAPK1PIK3CA | |
| SCHEMBL1548545 | 0.79 | ALDH1A1 (0.41) | ALDH1A1CYP3A4TSHRMAPK1PIK3CA | |
| SCHEMBL19142238 | 0.79 | CYP3A4 (0.38) | ALDH1A1RAPGEF4CYP3A4TSHRMAPK1 | |
| SCHEMBL29454259 | 0.75 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPK1GAAHTT | |
| SCHEMBL560909 | 0.75 | CYP3A4 (0.35) | ALDH1A1CYP3A4TSHRMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4295441-A | — | — | None | — | — | JP | disclosed |
| WO-2025101780-A1 | PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF | OCTANT, INC. (US) | 2025-05-15 | — | — | WO | disclosed |
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| US-20240067614-A1 | NOVEL COMPOUNDS | NRG THERAPEUTICS LTD. (GB) | 2024-02-29 | — | — | US | disclosed |
| US-20240067614-A1 | NOVEL COMPOUNDS | NRG THERAPEUTICS LTD. (GB) | 2024-02-29 | — | — | US | disclosed |
| EP-3700904-B1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | BAYER AG (DE) | 2023-07-19 | — | — | EP | disclosed |
| US-20230192629-A1 | METHODS OF SYNTHESIZING FARNESYL DIBENZODIAZEPINONES | AMO PHARMA LTD. (US) | 2023-06-22 | — | — | US | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |
| WO-2021243171-A1 | METHODS OF SYNTHESIZING FARNESYL DIBENZODIAZEPINONES | AMO PHARMA LTD (US) | 2021-12-02 | — | — | WO | disclosed |
| WO-2020216774-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-10-29 | — | — | WO | disclosed |
| US-20130053376-A1 | NOVEL TYROSINE KINASE INHIBITORS | CHEMBRIDGE COPRPORATION | 2013-02-28 | — | — | US | disclosed |
| US-20130053376-A1 | NOVEL TYROSINE KINASE INHIBITORS | CHEMBRIDGE COPRPORATION | 2013-02-28 | — | — | US | disclosed |
| US-20130053376-A1 | NOVEL TYROSINE KINASE INHIBITORS | CHEMBRIDGE COPRPORATION | 2013-02-28 | — | — | US | disclosed |
| EP-2262807-A1 | NOVEL TYROSINE KINASE INHIBITORS | ChemBridge Corporation (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009117097-A1 | NOVEL TYROSINE KINASE INHIBITORS | CHEMBRIDGE CORPORATION (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009117097-A1 | NOVEL TYROSINE KINASE INHIBITORS | CHEMBRIDGE CORPORATION (US) | 2009-09-24 | — | — | WO | disclosed |
| JP-H04295441-A | COMPOUND HAVING AROMATIC RING | OTSUKA PHARMACEUT CO LTD | 1992-10-20 | — | — | JP | disclosed |
| US-4338318-A | FUNGICIDE OR BACERICIDE TO TREAT PLANT DISEASES WITH A PHENYL URACIL | ZOECON CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |
| US-4297297-A | α-Cyano-β-(substituted-anilino)-N-ethoxycarbonylacrylamide intermediates | ZOECON CORP. (US) | 1981-10-27 | — | — | US | disclosed |
| US-4266056-A | FUNGICIDES, BACTERICIDES | ZOECON CORPORATION (US) | 1981-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067614-A1 | NOVEL COMPOUNDS | CYP11B1, CYP11B2, CXCR2 | ALDH1A1 478/4885RAPGEF4 3097/4885L3MBTL1 4306/4885 |
| US-20230192629-A1 | METHODS OF SYNTHESIZING FARNESYL DIBENZODIAZEPINONES | FNTB, FNTA, FDPS | ALDH1A1 1022/4885RAPGEF4 985/4885L3MBTL1 3660/4885 |
| US-20130053376-A1 | NOVEL TYROSINE KINASE INHIBITORS | ABL1, RET, TTBK1 | ALDH1A1 2215/4885RAPGEF4 2316/4885L3MBTL1 3978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.