Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.55 |
| ▸ | PTGFR | P43088 | 1/20 | 0.55 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.55 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.55 |
| ▸ | PTGIR | P43119 | 1/20 | 0.55 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PTPRG | P23470 | 2/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | CD38 | P28907 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253389 | 0.86 | KMT2A (0.51) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL3461077 | 0.82 | TSHR (0.51) | LMNAKDM4EALDH1A1NPC1MAPT | |
| SCHEMBL3461101 | 0.81 | ADRA1D (0.49) | LMNAKDM4EALDH1A1CD38KMT2A | |
| SCHEMBL28177161 | 0.79 | TBXA2R (0.54) | TBXA2RPTGER4PTGFRPTGER3PTGER2 | |
| SCHEMBL3461538 | 0.78 | LMNA (0.50) | LMNAKDM4EALDH1A1AURKARPS6KB1 | |
| SCHEMBL3459871 | 0.78 | MAPK8 (0.46) | LMNAKDM4EALDH1A1AURKARPS6KB1 | |
| SCHEMBL3461758 | 0.78 | CD38 (0.46) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL1004028 | 0.78 | TSHR (0.58) | KDM4EALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL11543797 | 0.77 | SLC6A2 (0.54) | TBXA2RPTGER1PTGER4PTGFRPTGER3 | |
| SCHEMBL7134588 | 0.77 | TSHR (0.54) | KDM4EALDH1A1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022157686-A1 | INHIBITORS OF ANOCTAMIN 6 PROTEIN AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-07-28 | — | — | WO | disclosed |
| US-7704995-B2 | Protein kinase modulators and methods of use | EXELIXIS, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| US-20060211709-A1 | Protein kinase modulators and methods of use | EXELIXIS, INC. | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211709-A1 | Protein kinase modulators and methods of use | GRK2, MAP4K2, MAPKAPK2 | TBXA2R 1015/4885PTGER1 1467/4885PTGER4 1845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.