Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PTPRG | P23470 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3461063 | 0.86 | TBXA2R (0.55) | KMT2AMEN1RECQLBLMTDP1 | |
| SCHEMBL21357052 | 0.83 | ALDH1A1 (0.61) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL4735612 | 0.80 | ALDH1A1 (0.54) | KMT2AMEN1RECQLBLMTDP1 | |
| SCHEMBL940131 | 0.79 | ALDH1A1 (0.60) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL5723969 | 0.78 | CYP19A1 (0.50) | KMT2ATAAR1L3MBTL1SLC6A5ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28193722 | 0.77 | ALDH1A1 (0.58) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL5724287 | 0.77 | DRD2 (0.50) | KMT2ATAAR1RPS6KB1AURKASLC6A5 | |
| SCHEMBL11782261 | 0.76 | SIRT2 (0.48) | KMT2ATAAR1L3MBTL1RPS6KB1AURKA | |
| SCHEMBL29818302 | 0.76 | SIRT2 (0.51) | KMT2ATAAR1RPS6KB1AURKAALDH1A1 | |
| SCHEMBL11245059 | 0.76 | IGF1R (0.54) | KMT2AMEN1RECQLBLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577291-A1 | Phenylethanolamine derivatives as beta-2 agonists | Pfizer Limited (GB) | 2005-09-21 | — | — | EP | disclosed |