SCHEMBL346288

SCHEMBL346288

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nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PDE4A P27815 1/20 0.37
USP2 O75604 1/20 0.35
SLCO1B1 Q9Y6L6 1/20 0.35
KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346929 1.00 TDP1 (0.41) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL26124162 0.93 LMNA (0.36) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL28448089 0.83 TDP1 (0.55) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL19951539 0.83 TDP1 (0.55) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL4278439 0.82 TDP1 (0.44) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL300611 0.82 TDP1 (0.44) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL10909683 0.81 TDP1 (0.43) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL60717 0.81 TDP1 (0.43) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL9682216 0.80 LMNA (0.35) TDP1LMNAL3MBTL1PDE4AUSP2
SCHEMBL9682220 0.80 LMNA (0.35) TDP1LMNAL3MBTL1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240198316-A1 SYNTHETIC POLYMERIC POROUS MEDIUM WITH HIERARCHICAL MULTIPLE LAYER STRUCTURE, ITS DESIGN, SYNTHESIS, MODIFICATION, AND LIQUID CHROMATOGRAPHIC APPLICATIONS SUZHOU SEPAX TECHNOLOGIES, INC. (CN) 2024-06-20 US claimed
EP-4337357-A1 SYNTHETIC POLYMERIC POROUS MEDIUM WITH HIERARCHICAL MULTIPLE LAYER STRUCTURE, ITS DESIGN, SYNTHESIS, MODIFICATION, AND LIQUID CHROMATOGRAPHIC APPLICATIONS Suzhou Sepax Technologies, Inc. (CN) 2024-03-20 EP claimed
CN-117377521-A Synthetic polymeric porous media with hierarchical multi-layer structure and design, synthesis, modification and liquid chromatography applications thereof 苏州赛分科技股份有限公司 2024-01-09 CN claimed
WO-2022253175-A1 SYNTHETIC POLYMERIC POROUS MEDIUM WITH HIERARCHICAL MULTIPLE LAYER STRUCTURE, ITS DESIGN, SYNTHESIS, MODIFICATION, AND LIQUID CHROMATOGRAPHIC APPLICATIONS SUZHOU SEPAX TECHNOLOGIES, INC (CN) 2022-12-08 WO claimed
WO-2022252071-A1 A SYNTHETIC POLYMERIC POROUS MEDIUM WITH HIERARCHICAL MULTIPLE LAYER STRUCTURE, ITS DESIGN, SYNTHESIS, MODIFICATION, AND LIQUID CHROMATOGRAPHIC APPLICATIONS SUZHOU SEPAX TECHNOLOGIES, INC (CN) 2022-12-08 WO claimed
US-9155685-B2 Low stress flowable dental composition DENTSPLY INTERNATIONAL INC. (US) 2015-10-13 US claimed
US-9138488-B2 Polysorbitol-based osmotically active transporter and gene therapy using same SNU R&DB FOUNDATION (KR) 2015-09-22 US claimed
US-20140348777-A1 Polysorbitol-Based Osmotically Active Transporter and Gene Therapy Using Same SNU R&DB FOUNDATION (KR) 2014-11-27 US claimed
US-8294975-B2 Automotive rearview mirror assembly DONNELLY CORPORATION (US) 2012-10-23 US claimed
US-20100110523-A1 AUTOMOTIVE REARVIEW MIRROR ASSEMBLY DONNELLY CORPORATION (US) 2010-05-06 US claimed
US-6627762-B1 Curable Henkel IP & Holding GmbH (DE) 2003-09-30 US claimed
US-6627720-B2 Monoethylenically unsaturated monomers are polymerized with at least one multiethylenically unsaturated monomer at high temperatures by free radical polymerization in a continuous reactor, without formation of highly crosslinked gels JOHNSON POLYMER, LLC 2003-09-30 US claimed
US-6265511-B1 BLEND OF DIVINYL MONOMER AND MONOETHYLENICALLY UNSATURATED MONOMER S. C. JOHNSON COMMERICAL MARKETS, INC. 2001-07-24 US claimed
US-6154306-A Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2000-11-28 US claimed
EP-0612826-B1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processing for making such solid films and devices DONNELLY CORP (US) 2000-10-04 EP claimed
EP-1004649-A2 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2000-05-31 EP claimed
US-6002511-A Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 1999-12-14 US claimed
EP-0612826-A1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processing for making such solid films and devices DONNELLY CORPORATION (US) 1994-08-31 EP claimed
US-5270415-A Balanced charge polymer and hydrophilic contact lens manufactured therefrom ALLERGAN INC. (US) 1993-12-14 US claimed
US-4082894-A COATING WITH PRIMER POLYMER, DRYING, CURING MELAMINE-TYPE RESIN COATING NIPPON SHEET GLASS CO., LTD. (JA) 1978-04-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140348777-A1 Polysorbitol-Based Osmotically Active Transporter and Gene Therapy Using Same SLC20A1, SLC34A1, SLC26A6 TDP1 1206/4885LMNA 1956/4885L3MBTL1 344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.