SCHEMBL3463284

SCHEMBL3463284

O=C(O)C1CCN[C@@H]1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 2/20 1.00
MEN1 O00255 1/20 0.75
BLM P54132 1/20 0.75
KMT2A Q03164 1/20 0.75
SLC1A1 P43005 1/20 0.45
ARG1 P05089 5/20 0.44
ARG2 P78540 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2177041 1.00 SLC1A2 (1.00) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL2177035 1.00 SLC1A2 (1.00) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL2177045 1.00 SLC1A2 (1.00) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL21402233 0.98 SLC1A2 (0.95) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL17743458 0.98 SLC1A2 (0.95) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL28347967 0.89 MEN1 (0.96) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL730491 0.86 MEN1 (1.00) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL6342925 0.86 MEN1 (1.00) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL730489 0.86 MEN1 (1.00) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL6342928 0.86 MEN1 (1.00) SLC1A2MEN1BLMKMT2ASLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010113035-A2 PEPTIDE-BASED BETA TURN MIMETICS UNIVERSITY OF MANITOBA (CA) 2010-10-07 WO disclosed
US-20100256333-A1 Peptide-Based Beta Turn Mimetics UNIVERSITY OF MANITOBA (CA) 2010-10-07 US disclosed
US-6858626-B2 Enzyme inhibitor; antiinflammatory agents; osteoporosis BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2005-02-22 US disclosed
US-20030139597-A1 Novel Cyclic hydroxamic acid as metalloproteinase inhibitors XUE CHU-BIAO (US) 2003-07-24 US disclosed
US-6429213-B1 ANTIINFLAMMATORY AGENTS, ANTIARTHRITIS AGENTS BRISTOL-MYERS SQUIBB PHARMA COMPANY 2002-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256333-A1 Peptide-Based Beta Turn Mimetics VIP, PTMA, PREP SLC1A2 3355/4885MEN1 218/4885BLM 2259/4885
US-20030139597-A1 Novel Cyclic hydroxamic acid as metalloproteinase inhibitors MMP9, MMP2, MMP25 SLC1A2 649/4885MEN1 3733/4885BLM 4342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.