SCHEMBL2177041

SCHEMBL2177041

O=C(O)C1CCNC1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 2/20 1.00
MEN1 O00255 1/20 0.75
BLM P54132 1/20 0.75
KMT2A Q03164 1/20 0.75
SLC1A1 P43005 1/20 0.45
ARG1 P05089 5/20 0.44
ARG2 P78540 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3463284 1.00 SLC1A2 (1.00) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL2177035 1.00 SLC1A2 (1.00) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL2177045 1.00 SLC1A2 (1.00) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL21402233 0.98 SLC1A2 (0.95) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL17743458 0.98 SLC1A2 (0.95) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL28347967 0.89 MEN1 (0.96) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL730491 0.86 MEN1 (1.00) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL6342925 0.86 MEN1 (1.00) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL730489 0.86 MEN1 (1.00) SLC1A2MEN1BLMKMT2ASLC1A1
SCHEMBL6342928 0.86 MEN1 (1.00) SLC1A2MEN1BLMKMT2ASLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
CN-102548640-B Carbon dioxide absorbing liquid TOSHIBA KK 2015-02-18 CN claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
EP-2170260-A1 AZO DERIVATIVES CONTAINING A PYRAZOLINONE UNIT FOR DYEING KERATIN FIBRES L'Oreal (FR) 2010-04-07 EP claimed
WO-2009000753-A1 AZO DERIVATIVES CONTAINING A PYRAZOLINONE UNIT FOR DYEING KERATIN FIBRES L'OREAL (FR) 2008-12-31 WO claimed
US-20070007489-A1 Heat transfer medium composition SHISHIAI-KABUSHIKIGAISHA (JP) 2007-01-11 US claimed
EP-1698678-A1 HEAT CARRIER COMPOSITION Shishiai-Kabushikigaisha (JP) 2006-09-06 EP claimed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 WO disclosed
CN-106794264-B Conjugates comprising neurotensin receptor ligands and uses thereof 3B制药有限公司 2021-03-23 CN disclosed
US-10799605-B2 Conjugate comprising a neurotensin receptor ligand and use thereof 3B PHARMACEUTICALS GMBH (DE) 2020-10-13 US disclosed
US-7491724-B2 Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases INCYTE CORPORATION (US) 2009-02-17 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed
US-20080167288-A1 Substituted cyclic hydroxamates as lnhibitors of matrix metalloproteinases LNCYTE CORPORATION (US) 2008-07-10 US disclosed
US-20070007489-A1 Heat transfer medium composition SHISHIAI-KABUSHIKIGAISHA (JP) 2007-01-11 US disclosed
EP-1698678-A1 HEAT CARRIER COMPOSITION Shishiai-Kabushikigaisha (JP) 2006-09-06 EP disclosed
US-20050113344-A1 Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases INCYTE CORPORATION 2005-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 SLC1A2 4244/4885MEN1 2029/4885BLM 3099/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB SLC1A2 4811/4885MEN1 452/4885BLM 350/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA SLC1A2 3491/4885MEN1 748/4885BLM 1845/4885
US-10799605-B2 Conjugate comprising a neurotensin receptor ligand and use thereof NTSR1, NTSR2, TAAR1 SLC1A2 89/4885MEN1 551/4885BLM 4827/4885
US-20080167288-A1 Substituted cyclic hydroxamates as lnhibitors of matrix metalloproteinases MMP25, MMP9, MMP24 SLC1A2 2201/4885MEN1 3782/4885BLM 3026/4885
US-20050113344-A1 Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases MMP25, MMP2, MMP14 SLC1A2 2042/4885MEN1 3168/4885BLM 2877/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA SLC1A2 333/4885MEN1 2921/4885BLM 1518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.