SCHEMBL3463774

SCHEMBL3463774

C=COC(CN)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.42
KIF11 P52732 6/20 0.38
HTT P42858 1/20 0.37
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
KCNN4 O15554 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.32
MAPK1 P28482 1/20 0.31
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2065992 0.72 TAAR1 (0.52) TAAR1KIF11KCNN4SMN1; SMN2MAPK1
SCHEMBL25911720 0.72 KIF11 (0.40) KIF11HTTALDH1A1TSHRKCNN4
SCHEMBL662477 0.69 TAAR1 (0.48) TAAR1KIF11ALDH1A1KCNN4SMN1; SMN2
SCHEMBL4521012 0.68 MAPK1 (0.56) TAAR1HTTALDH1A1TSHRKCNN4
SCHEMBL4169444 0.68 MAPK1 (0.44) TAAR1ALDH1A1TSHRKCNN4MAPK1
SCHEMBL10456259 0.68 MAPK1 (0.34) HTTALDH1A1TSHRKCNN4MAPK1
SCHEMBL4395774 0.68 TAAR1 (0.42) TAAR1KIF11HTTALDH1A1TSHR
SCHEMBL28837984 0.67 TAAR1 (0.46) TAAR1KIF11ALDH1A1SMN1; SMN2MAPK1
SCHEMBL3121099 0.67 MAPK1 (0.43) TAAR1ALDH1A1TSHRKCNN4SMN1; SMN2
SCHEMBL9636274 0.67 ALDH1A1 (0.34) HTTALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8300300-B2 Particle for display, particle dispersion liquid for display, display medium, and display device FUJI XEROX CO., LTD. (JP) 2012-10-30 US disclosed
US-20100073280-A1 PARTICLE FOR DISPLAY, PARTICLE DISPERSION LIQUID FOR DISPLAY, DISPLAY MEDIUM, AND DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2010-03-25 US disclosed
US-5724629-A Liquid developer monitoring device, liquid developer controlling system, and image forming apparatus using same MINOLTA CO., LTD. (JP) 1998-03-03 US disclosed