Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 7/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786495 | 0.84 | KIF11 (0.46) | TAAR1KIF11KCNN4SMN1; SMN2KCNH2 | |
| SCHEMBL9194628 | 0.83 | KCNN4 (0.40) | TAAR1KIF11KCNN4MAPK1ALDH1A1 | |
| SCHEMBL14127315 | 0.79 | KCNN4 (0.38) | TAAR1KIF11KCNN4MAPK1ALDH1A1 | |
| SCHEMBL663136 | 0.79 | ALDH1A1 (0.39) | TAAR1KIF11KCNN4MAPK1ALDH1A1 | |
| SCHEMBL4058230 | 0.79 | TAAR1 (0.48) | TAAR1KIF11KCNN4MAPK1SMN1; SMN2 | |
| SCHEMBL2065992 | 0.78 | TAAR1 (0.52) | TAAR1KIF11KCNN4MAPK1SMN1; SMN2 | |
| SCHEMBL3663151 | 0.78 | MAPK1 (0.40) | TAAR1KIF11KCNN4MAPK1ALDH1A1 | |
| SCHEMBL15357624 | 0.76 | LMNA (0.44) | TAAR1KIF11KCNN4MAPK1ALDH1A1 | |
| SCHEMBL5509055 | 0.76 | MAPT (0.43) | KIF11KCNN4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6155774 | 0.74 | KCNN4 (0.44) | TAAR1KIF11KCNN4MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351730-B1 | ETHOXY DIPHENYL ETHANE DERIVATES, PREPARATION PROCESSES AND USES THEREOF | SHANGHAI ECUST BIOMEDICINE CO LTD (CN) | 2014-07-30 | — | — | EP | disclosed |
| CN-102245560-B | Ethoxy diphenyl ethane derivates, preparation processes and uses thereof | SHANGHAI ECUST BIOMEDICINE CO LTD | 2014-04-16 | — | — | CN | disclosed |
| US-20120046492-A1 | Ethoxy Diphenyl Ethane Derivatives, Preparation Processes and Uses Thereof | Zhejiang Wild Wind Pharmaceutical Co., Ltd. (CN) | 2012-02-23 | — | — | US | disclosed |
| CN-102245560-A | Ethoxy diphenyl ethane derivates, preparation processes and uses thereof | SHANGHAI ECUST BIOMEDICINE CO | 2011-11-16 | — | — | CN | disclosed |
| EP-2351730-A1 | ETHOXY DIPHENYL ETHANE DERIVATES, PREPARATION PROCESSES AND USES THEREOF | Shanghai Ecust Biomedicine Co., Ltd (CN) | 2011-08-03 | — | — | EP | disclosed |
| CN-101723813-A | Ethoxy diphenyl ethane derivative and preparation method and application thereof | SHANGHAI ECUST BIOMEDICINE CO | 2010-06-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046492-A1 | Ethoxy Diphenyl Ethane Derivatives, Preparation Processes and Uses Thereof | TUBB1, TUBB, TUBB3 | TAAR1 1915/4885KIF11 1226/4885KCNN4 4149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.