SCHEMBL9636274

SCHEMBL9636274

C=COCC(OC=C)(OC=C)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.33
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28706287 0.73 ALDH1A1 (0.42) ALDH1A1TSHRHTTMEN1KMT2A
SCHEMBL28774519 0.72 KCNN4 (0.33) ALDH1A1TSHRMEN1LMNAKMT2A
SCHEMBL28691442 0.70 ALDH1A1 (0.40) ALDH1A1TSHRHTTMEN1KMT2A
SCHEMBL25911720 0.70 KIF11 (0.40) ALDH1A1TSHRHTTMEN1KMT2A
SCHEMBL4521012 0.67 MAPK1 (0.56) ALDH1A1TSHRHTTKMT2AMAPK1
SCHEMBL4169444 0.67 MAPK1 (0.44) ALDH1A1TSHRKMT2AMAPK1
SCHEMBL10456259 0.67 MAPK1 (0.34) ALDH1A1TSHRHTTMAPK1
SCHEMBL3463774 0.67 TAAR1 (0.42) ALDH1A1TSHRHTTMAPK1
SCHEMBL3121099 0.65 MAPK1 (0.43) ALDH1A1TSHRKMT2AMAPK1
SCHEMBL30935540 0.65 KIF11 (0.55) ALDH1A1TSHRHTTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5102966-A Addition polymerization of unsaturated ethers using an unsaturated alkenyl polyether adduct as initiator and a cation-donating compound SEKISUI CHEMICAL CO., LTD. (JP) 1992-04-07 US disclosed