Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.48 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29576829 | 1.00 | HDAC3 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9380333 | 0.83 | CA2 (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Carbazole SCHEMBL28454963 | 0.83 | ALDH1A1 (0.48) | CNR1 | |
| SCHEMBL329715 | 0.75 | AGXT (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16482581 | 0.74 | F9 (0.54) | — | |
| SCHEMBL845603 | 0.74 | APP (0.63) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29732980 | 0.74 | APP (0.63) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL18878582 | 0.73 | CYP2A6 (0.41) | CYP2A6APP | |
| SCHEMBL7632717 | 0.73 | AGXT (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15391504 | 0.73 | ESR1 (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 512 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751472-A | Fluorescein derivative and preparation method and application thereof | 湖北新德晟材料科技有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-115716837-B | Preparation method and application of quaternary ammonium salt template agent and titanium silicalite molecular sieve | 万华化学集团股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118221736-A | Synthesis method of bis (2-benzothienyl) phosphorus chloride | 浙江九洲药业股份有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-111278837-B | Hydrocarbon-soluble halogen and thiol/magnesium exchange reagent | 雅宝德国有限责任公司 | 2024-04-09 | — | — | CN | claimed |
| CN-117776830-A | Full deuteration preparation method of polycyclic aromatic hydrocarbon | 宁波萃英化学技术有限公司 | 2024-03-29 | — | — | CN | claimed |
| EP-3688000-B1 | HYDROCARBON-SOLUBLE HALOGEN AND THIOLATE/MAGNESIUM EXCHANGE REAGENTS | ALBEMARLE GERMANY GMBH (DE) | 2023-11-08 | — | — | EP | claimed |
| CN-116284134-A | Self-assembled hole transport material containing benzothiophene element, synthesis method and application | 西湖大学 | 2023-06-23 | — | — | CN | claimed |
| WO-2022205592-A1 | BENZOTHIOPHENE BENZO FIVE-MEMBERED HETEROCYCLE MATERIAL, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 北京大学深圳研究生院 | 2022-10-06 | — | — | WO | claimed |
| US-11236113-B2 | Hydrocarbon-soluble halogen and thiolate/magnesium exchange reagents | ALBEMARLE GERMANY GMBH (DE) | 2022-02-01 | — | — | US | claimed |
| CN-113121560-A | Benzothienobenzo five-membered heterocyclic material and preparation method and application thereof | 北京大学深圳研究生院 | 2021-07-16 | — | — | CN | claimed |
| EP-3688000-A1 | HYDROCARBON-SOLUBLE HALOGEN AND THIOLATE/MAGNESIUM EXCHANGE REAGENTS | Albemarle Germany GmbH (DE) | 2020-08-05 | — | — | EP | claimed |
| US-20200239496-A1 | Hydrocarbon-Soluble Halogen and Thiolate/Magnesium Exchange Reagents | Ludwig-Maximilians-Universitat München (DE) | 2020-07-30 | — | — | US | claimed |
| CN-111278837-A | Hydrocarbon-soluble halogen and thiolate/magnesium exchange reagents | 雅宝德国有限责任公司 | 2020-06-12 | — | — | CN | claimed |
| CN-208599203-U | Bromobenzothiophene vacuum concentration equipment | 郑州凡尔赛特化工有限公司 | 2019-03-15 | — | — | CN | claimed |
| CN-208599224-U | Bromobenzothiophene extraction equipment | 郑州凡尔赛特化工有限公司 | 2019-03-15 | — | — | CN | claimed |
| CN-108083393-A | The graphite electrode modified based on PbO-NiO-MgO and thiophene | 光合强化（北京）生物科技有限公司 | 2018-05-29 | — | — | CN | claimed |
| CN-103261189-B | Amino-pyrrolidine-azetidine diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV | 2015-01-28 | — | — | CN | claimed |
| US-12391659-B2 | Benzothiazole and related compounds | SPINOGENIX, INC. (US) | 2025-08-19 | — | — | US | disclosed |
| US-4249014-A | ANALGESICS, ANTISPASMODICS, ANTIINFLAMMATORY VASODILATORS | INNOTHERA (FR) | 1981-02-03 | — | — | US | disclosed |
| US-4186136-A | COAGULANTS, ANTISPASMODIC AGENTS, ANALGESICS, ANTIINGLAMMATORY AGENTS, VASODILATION | INNOTHERA (FR) | 1980-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239496-A1 | Hydrocarbon-Soluble Halogen and Thiolate/Magnesium Exchange Reagents | OR10J3, MSRB3, SLC39A3 | HDAC3 3960/4885HDAC4 4171/4885HDAC1 3899/4885 |
| US-12391659-B2 | Benzothiazole and related compounds | BACE1, APP, BACE2 | HDAC3 4490/4885HDAC4 3369/4885HDAC1 4128/4885 |
| US-11236113-B2 | Hydrocarbon-soluble halogen and thiolate/magnesium exchange reagents | MSRB3, OR10J3, GFER | HDAC3 4109/4885HDAC4 4214/4885HDAC1 3809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.