Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | COMT | P21964 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSH | P09668 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405953 | 0.80 | KMT2A (0.57) | KMT2AOPRK1COMTCTSBCTSH | |
| SCHEMBL9976737 | 0.77 | SMN1; SMN2 (0.36) | KMT2AALDH1A1KDM4EHPGDMAPT | |
| Phenol SCHEMBL4398891 | 0.77 | KMT2A (0.53) | KMT2AOPRK1COMTCTSBCTSH | |
| SCHEMBL3462635 | 0.76 | HIPK2 (0.37) | LMNAKIF11NPC1RAB9ATP53 | |
| SCHEMBL31032819 | 0.74 | KMT2A (0.62) | KMT2AOPRK1CTSBCTSHMETAP2 | |
| SCHEMBL3462526 | 0.74 | KMT2A (0.62) | KMT2AOPRK1CTSBCTSHMETAP2 | |
| SCHEMBL17806567 | 0.74 | KIF11 (0.44) | ALDH1A1KDM4EHPGDALOX15HSD17B10 | |
| SCHEMBL3275602 | 0.73 | KMT2A (0.77) | KMT2AOPRK1CTSBCTSHMETAP2 | |
| SCHEMBL7171554 | 0.71 | KMT2A (0.74) | KMT2AOPRK1CTSBCTSHMETAP2 | |
| SCHEMBL8090833 | 0.70 | KMT2A (1.00) | KMT2AOPRK1CTSBCTSHMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470208-B2 | Organometallic complexes | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-25 | — | — | US | disclosed |
| US-8470208-B2 | Organometallic complexes | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-25 | — | — | US | disclosed |
| US-8470208-B2 | Organometallic complexes | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-25 | — | — | US | disclosed |
| EP-1979437-B1 | ORGANOMETALLIC COMPLEXES | DU PONT (US) | 2013-04-10 | — | — | EP | disclosed |
| EP-1979437-B1 | ORGANOMETALLIC COMPLEXES | DU PONT (US) | 2013-04-10 | — | — | EP | disclosed |
| US-20100264380-A1 | Organometallic complexes | E. I. DU PONT DE NEMOURS AND COMPANY | 2010-10-21 | — | — | US | disclosed |
| US-20100264380-A1 | Organometallic complexes | E. I. DU PONT DE NEMOURS AND COMPANY | 2010-10-21 | — | — | US | disclosed |
| US-20100264380-A1 | Organometallic complexes | E. I. DU PONT DE NEMOURS AND COMPANY | 2010-10-21 | — | — | US | disclosed |
| EP-1979437-A2 | ORGANOMETALLIC COMPLEXES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007087223-A2 | ORGANOMETALLIC COMPLEXES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-08-02 | — | — | WO | disclosed |
| WO-2007087223-A2 | ORGANOMETALLIC COMPLEXES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100264380-A1 | Organometallic complexes | GSTO1, CYP4F12, CYP4F3 | KMT2A 369/4885OPRK1 2075/4885COMT 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.