Phenol

Phenol

SCHEMBL4398891

Cc1ccc2c(-c3ccccc3)ccc(O)c2n1.Cc1ccc2c(-c3ccccc3)ccc(O)c2n1.Oc1ccccc1.[Ga]

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
OPRK1 P41145 1/20 0.53
COMT P21964 1/20 0.44
CTSB P07858 1/20 0.44
CTSH P09668 1/20 0.44
METAP2 P50579 1/20 0.42
ESR2 Q92731 2/20 0.39
ALOX5 P09917 1/20 0.39
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.38
MAPT P10636 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4405953 0.95 KMT2A (0.57) KMT2AOPRK1COMTCTSBCTSH
Phenol SCHEMBL28074113 0.79 KDM4E (0.45) KMT2AMETAP2ESR2ALDH1A1HPGD
SCHEMBL3464002 0.77 KMT2A (0.53) KMT2AOPRK1COMTCTSBCTSH
SCHEMBL6639684 0.74 CRHR1 (0.48) KMT2AOPRK1COMTMETAP2ESR2
8-Hydroxy Quinaldine SCHEMBL4386958 0.73 METAP2 (0.79) KMT2AOPRK1COMTMETAP2ALDH1A1
SCHEMBL3275602 0.73 KMT2A (0.77) KMT2AOPRK1CTSBCTSHMETAP2
Phenol SCHEMBL4404354 0.73 COMT (0.66) COMTMETAP2ALDH1A1MAPTNPC1
SCHEMBL20777888 0.73 ACACA (0.41) ALDH1A1HPGDMAPTCYP2D6CYP2C9
SCHEMBL6080627 0.73 MMP2 (0.53) KMT2ACOMTMAPTALOX15RAB9A
SCHEMBL8034930 0.73 ADORA1 (0.51) MAPTNPC1ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090156827-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT TOYO INK MFG. CO., LTD. (JP) 2009-06-18 US disclosed
EP-2025733-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ORGANIC ELECTROLUMINESCENCE ELEMENT TOYO INK MFG. CO., LTD. (JP) 2009-02-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156827-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT ELP1, ELAVL1, ELF3 KMT2A 905/4885OPRK1 2013/4885COMT 3546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.