Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12210461 | 0.84 | TAAR1 (0.42) | ALDH1A1GAAMAPTCYP2D6ALOX15 | |
| SCHEMBL11384732 | 0.80 | ALDH1A1 (0.44) | ALDH1A1GAAMAPTGLACYP2D6 | |
| SCHEMBL11095079 | 0.79 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTGLACYP2D6 | |
| SCHEMBL21035429 | 0.79 | CYP3A4 (0.37) | ALDH1A1GAAMAPTGLACYP2D6 | |
| SCHEMBL9860607 | 0.79 | ALDH1A1 (0.47) | ALDH1A1GAAMAPTGLACYP2D6 | |
| SCHEMBL11974261 | 0.77 | MAPT (0.39) | ALDH1A1GAAMAPTCYP2D6ALOX15 | |
| SCHEMBL1751672 | 0.77 | AHR (0.53) | ALDH1A1GAAMAPTCYP2D6CYP1A2 | |
| SCHEMBL24192821 | 0.75 | CYP3A4 (0.38) | ALDH1A1GAAMAPTGLACYP2D6 | |
| SCHEMBL172849 | 0.75 | CYP1A2 (0.55) | ALDH1A1GAAMAPTCYP2D6ALOX15 | |
| SCHEMBL23771835 | 0.75 | SMAD3 (0.38) | CYP2D6ALOX15CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190161451-A1 | HERBICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2019-05-30 | — | — | US | disclosed |
| WO-2018019554-A1 | HERBICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2018-02-01 | — | — | WO | disclosed |
| EP-2185547-B1 | IMIDAZOLONE DERIVATIVES, PREPARATION METHOD THEREOF AND BIOLOGICAL USE OF SAME | UNIV RENNES (FR) | 2017-07-19 | — | — | EP | disclosed |
| US-8563588-B2 | Imidazolone derivatives, method for the preparation thereof and biological applications | UNIVERSITE DE RENNES 1 (FR) | 2013-10-22 | — | — | US | disclosed |
| US-20100240656-A1 | COMPOUNDS AS HSP90 INHIBITORS | ORYZON GENOMICS, S.A. (ES) | 2010-09-23 | — | — | US | disclosed |
| US-20100216855-A1 | IMIDAZAOLONE DERIVATIVES,PREPARATION THEREOF AND BIOLOGICAL USE OF SAME | UNIVERSITE DE RENNES (FR) | 2010-08-26 | — | — | US | disclosed |
| US-20100216855-A1 | IMIDAZAOLONE DERIVATIVES,PREPARATION THEREOF AND BIOLOGICAL USE OF SAME | UNIVERSITE DE RENNES (FR) | 2010-08-26 | — | — | US | disclosed |
| EP-2183221-A1 | NEW COMPOUNDS AS HSP90 INHIBITORS | Crystax Pharmaceuticals S.L. (ES) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009007399-A1 | NEW COMPOUNDS AS HSP90 INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2009-01-15 | — | — | WO | disclosed |
| US-5475024-A | Useful in treating liver disease | EISAI CO., LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| US-5292901-A | Benzodioxole derivatives | EISAI CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0281098-B1 | BENZODIOXOLE DERIVATIVES, COMPOSITIONS COMPRISING THE SAME, AND THE USE OF THE SAME FOR THE MANUFACTURE OF MEDICAMENTS | Eisai Co., Ltd. (JP) | 1992-11-25 | — | — | EP | disclosed |
| US-5110956-A | Liver disorders | EISAI CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |
| EP-0281098-A1 | Benzodioxole derivatives, compositions comprising the same, and the use of the same for the manufacture of medicaments | Eisai Co., Ltd. (JP) | 1988-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216855-A1 | IMIDAZAOLONE DERIVATIVES,PREPARATION THEREOF AND BIOLOGICAL USE OF SAME | NR0B2, HRH1, HRH2 | ALDH1A1 623/4885GAA 4683/4885MAPT 4789/4885 |
| US-20190161451-A1 | HERBICIDAL PYRIMIDINE COMPOUNDS | DPYD, TYMP, DHFR | ALDH1A1 216/4885GAA 414/4885MAPT 2448/4885 |
| US-20100240656-A1 | COMPOUNDS AS HSP90 INHIBITORS | HSP90AB1, HSP90AB2P, HSP90AA1 | ALDH1A1 1875/4885GAA 2505/4885MAPT 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.