Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | BCR | P11274 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.56 |
| ▸ | CDK4 | P11802 | 1/20 | 0.54 |
| ▸ | CCND1 | P24385 | 1/20 | 0.54 |
| ▸ | JUN | P05412 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27992 | 1.00 | TRPA1 (1.00) | TRPA1NFKB1CA1CA2CA4 | |
| SCHEMBL27991 | 1.00 | TRPA1 (1.00) | TRPA1NFKB1CA1CA2CA4 | |
| SCHEMBL30218372 | 1.00 | TRPA1 (1.00) | TRPA1NFKB1CA1CA2CA4 | |
| Potassium SCHEMBL9419818 | 0.98 | TRPA1 (0.95) | TRPA1NFKB1CA1CA2CA4 | |
| SCHEMBL9419834 | 0.98 | TRPA1 (0.95) | TRPA1NFKB1CA1CA2CA4 | |
| SCHEMBL9419828 | 0.98 | TRPA1 (0.95) | TRPA1NFKB1CA1CA2CA4 | |
| SCHEMBL9419830 | 0.98 | TRPA1 (0.95) | TRPA1NFKB1CA1CA2CA4 | |
| SCHEMBL9419814 | 0.98 | TRPA1 (0.95) | TRPA1NFKB1CA1CA2CA4 | |
| SCHEMBL9419815 | 0.98 | TRPA1 (0.95) | TRPA1NFKB1CA1CA2CA4 | |
| Formaldehyde SCHEMBL20525513 | 0.94 | TRPA1 (0.88) | TRPA1NFKB1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010049390-A1 | COSMETIC AND DERMATOLOGICAL COMPOSITIONS FOR THE REDUCTION OF FACIAL EXPRESSION WRINKLES | HENKEL AG & CO. KGAA (DE) | 2010-05-06 | — | — | WO | claimed |
| EP-2238968-B1 | Skin treatment fighting skin aging | HENKEL AG & CO KGAA (DE) | 2018-05-02 | — | — | EP | disclosed |
| WO-2010049390-A1 | COSMETIC AND DERMATOLOGICAL COMPOSITIONS FOR THE REDUCTION OF FACIAL EXPRESSION WRINKLES | HENKEL AG & CO. KGAA (DE) | 2010-05-06 | — | — | WO | disclosed |
| US-7507851-B2 | Halocombstatins and methods of synthesis thereof | ARIZONA BOARD OF REGENTS, A STATE CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2009-03-24 | — | — | US | disclosed |
| US-20080119649-A1 | HALOCOMBSTATINS AND METHODS OF SYNTHESIS THEREOF | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY | 2008-05-22 | — | — | US | disclosed |
| US-20070167412-A1 | HALOCOMBSTATINS AND METHODS OF SYNTHESIS THEREOF | ARIZONA BOARD OF REGENTS (US) | 2007-07-19 | — | — | US | disclosed |
| EP-1802560-A2 | HALOCOMBSTATINS AND METHODS OF SYNTHESIS THEREOF | Arizona Board Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University (US) | 2007-07-04 | — | — | EP | disclosed |
| US-7223747-B2 | Halocombstatins and methods of synthesis thereof | ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2007-05-29 | — | — | US | disclosed |
| WO-2006036743-A2 | HALOCOMBSTATINS AND METHODS OF SYNTHESIS THEREOF | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2006-04-06 | — | — | WO | disclosed |
| US-20050176688-A1 | Halocombstatins and methods of synthesis thereof | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119649-A1 | HALOCOMBSTATINS AND METHODS OF SYNTHESIS THEREOF | TUBB3, TUBB8B, TUBB8 | TRPA1 4108/4885NFKB1 4001/4885CA1 1904/4885 |
| US-20070167412-A1 | HALOCOMBSTATINS AND METHODS OF SYNTHESIS THEREOF | TUBB3, TUBB8B, TUBB8 | TRPA1 4108/4885NFKB1 4001/4885CA1 1904/4885 |
| US-20050176688-A1 | Halocombstatins and methods of synthesis thereof | TUBB3, TUBB8B, TUBB8 | TRPA1 4108/4885NFKB1 4001/4885CA1 1904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.