Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 9/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467076 | 0.84 | THRB (0.36) | THRBMAPTALDH1A1CYP2C9HPGD | |
| SCHEMBL2821656 | 0.83 | TBXAS1 (0.36) | THRBMAPTALDH1A1CYP2C9HPGD | |
| SCHEMBL2820072 | 0.79 | ALDH1A1 (0.35) | THRBMAPTALDH1A1CYP2C9HPGD | |
| SCHEMBL2821658 | 0.79 | MAPT (0.42) | THRBMAPTALDH1A1CYP2C9HPGD | |
| SCHEMBL2822454 | 0.75 | PPARA (0.40) | THRBMAPTALDH1A1CYP2C9HPGD | |
| SCHEMBL2819988 | 0.71 | SMN1; SMN2 (0.41) | THRBMAPTALDH1A1CYP2C9HPGD | |
| SCHEMBL2820147 | 0.71 | ALDH1A1 (0.37) | MAPTALDH1A1CYP2C9HPGDKDM4E | |
| SCHEMBL2820153 | 0.71 | ALDH1A1 (0.37) | MAPTALDH1A1CYP2C9HPGDKDM4E | |
| SCHEMBL2821913 | 0.71 | ALDH1A1 (0.37) | MAPTALDH1A1CYP2C9HPGDKDM4E | |
| SCHEMBL12240275 | 0.69 | KMT2A (0.53) | MAPTALDH1A1HPGDPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010071813-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-α | ARYX THERAPEUTICS, INC. (US) | 2010-06-24 | — | — | WO | claimed |