Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334991 | 0.82 | C5AR1 (0.55) | BRD4C5AR1MCHR1KCNN4HTR2C | |
| SCHEMBL29788194 | 0.76 | TP53 (0.53) | C5AR1KCNN4HTR2C | |
| SCHEMBL13370771 | 0.76 | TP53 (0.53) | C5AR1KCNN4HTR2C | |
| SCHEMBL8222244 | 0.75 | MCHR1 (0.47) | BRD4C5AR1MCHR1KCNN4HTR2C | |
| SCHEMBL15473213 | 0.75 | ADRB2 (0.48) | FEN1ADRA2AADRA2BADRA2CHTR2A | |
| SCHEMBL29699363 | 0.75 | PTGER1 (0.48) | BRD4C5AR1MCHR1KCNN4CHRM3 | |
| SCHEMBL18071656 | 0.75 | TP53 (0.45) | FEN1ADRA2AADRA2BADRA2C | |
| SCHEMBL12958354 | 0.74 | IDO1 (0.48) | MCHR1FEN1ADRA2AADRA2BADRA2C | |
| SCHEMBL27996084 | 0.74 | PARP10 (0.52) | — | |
| SCHEMBL12968482 | 0.74 | CYP1A2 (0.50) | FEN1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240678-A1 | LEUKOTRIENE B4 INHIBITORS | DOMINIQUE ROMYR | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240678-A1 | LEUKOTRIENE B4 INHIBITORS | LTB4R2, LTB4R, LTC4S | KCNH2 2945/4885BRD4 2322/4885C5AR1 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.