Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 3/20 | 0.65 |
| ▸ | MMP13 | P45452 | 3/20 | 0.65 |
| ▸ | MME | P08473 | 3/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924636 | 0.83 | MMP12 (0.65) | MMP12MMP13MMEXDHSLC22A12 | |
| SCHEMBL7928277 | 0.82 | MMP12 (0.64) | MMP12MMP13MMEXDHSLC22A12 | |
| SCHEMBL7932591 | 0.81 | MMP12 (0.63) | MMP12MMP13MMEXDHSLC22A12 | |
| SCHEMBL5613445 | 0.79 | MMP12 (1.00) | MMP12MMP13MMEXDHSLC22A12 | |
| SCHEMBL5879179 | 0.79 | CYP2C19 (0.55) | MMP12MMP13MMEMCHR1XDH | |
| SCHEMBL12646477 | 0.78 | FFAR1 (0.70) | MMP12MMP13MMEXDHSLC22A12 | |
| SCHEMBL3467200 | 0.77 | MMP12 (0.60) | MMP12MMP13MMEXDHSLC22A12 | |
| SCHEMBL7923446 | 0.77 | MMP12 (0.57) | MMP12MMP13MMEMCHR1XDH | |
| SCHEMBL14672105 | 0.76 | MMP12 (0.62) | MMP12MMP13MMEXDHSLC22A12 | |
| SCHEMBL7917889 | 0.75 | MMP12 (0.55) | MMP12MMP13MMEXDHSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | claimed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |