Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.60 |
| ▸ | MMP13 | P45452 | 2/20 | 0.60 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 7/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | CTSC | P53634 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924636 | 0.93 | MMP12 (0.65) | MMP12MMP13FOLH1MMEFFAR1 | |
| SCHEMBL3468280 | 0.87 | MMP12 (0.53) | MMP12MMP13FOLH1MMEFFAR1 | |
| SCHEMBL3466777 | 0.86 | MMP12 (0.54) | MMP12MMP13FOLH1MMEFFAR1 | |
| SCHEMBL3467425 | 0.86 | MMP12 (0.54) | MMP12MMP13FOLH1MMEFFAR1 | |
| SCHEMBL3466325 | 0.84 | FFAR1 (0.57) | MMP12MMP13FOLH1FFAR1ADAMTS4 | |
| SCHEMBL7928277 | 0.83 | MMP12 (0.64) | MMP12MMP13FOLH1MMEFFAR1 | |
| SCHEMBL7932591 | 0.82 | MMP12 (0.63) | MMP12MMP13FOLH1MMEFFAR1 | |
| SCHEMBL7923446 | 0.80 | MMP12 (0.57) | MMP12MMP13FOLH1MMEFFAR1 | |
| SCHEMBL3465875 | 0.77 | MMP12 (0.65) | MMP12MMP13MMEFFAR1XDH | |
| SCHEMBL12646477 | 0.77 | FFAR1 (0.70) | MMP12MMP13MMEFFAR1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | claimed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |