Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.55 |
| ▸ | MMP13 | P45452 | 2/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 6/20 | 0.41 |
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924568 | 0.92 | MMP12 (0.48) | MMP12MMP13FOLH1MMP3MMP2 | |
| SCHEMBL7928277 | 0.90 | MMP12 (0.64) | MMP12MMP13FOLH1MMEMMP3 | |
| SCHEMBL7932591 | 0.88 | MMP12 (0.63) | MMP12MMP13FOLH1MMEMMP3 | |
| SCHEMBL3469955 | 0.82 | SLC13A5 (0.46) | MMP3MMP2AKR1B1 | |
| SCHEMBL7924636 | 0.82 | MMP12 (0.65) | MMP12MMP13FOLH1MMEMMP2 | |
| SCHEMBL1858161 | 0.81 | KMT2A (0.52) | FFAR1AKR1B1KMT2A | |
| SCHEMBL3467249 | 0.81 | MMP12 (0.54) | MMP12MMP13FOLH1MMP3MMP2 | |
| SCHEMBL1859538 | 0.80 | MMP12 (0.47) | MMP12MMP3MMP2 | |
| SCHEMBL7929539 | 0.79 | MMP2 (0.48) | MMP3MMP2FFAR1AKR1B1KMT2A | |
| SCHEMBL7926499 | 0.79 | PTPN1 (0.53) | MMP3MMP2FFAR1AKR1B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |