Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.64 |
| ▸ | MMP13 | P45452 | 2/20 | 0.64 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932591 | 0.99 | MMP12 (0.63) | MMP12MMP13FOLH1MMEMMP2 | |
| SCHEMBL3467249 | 0.91 | MMP12 (0.54) | MMP12MMP13FOLH1MMP2MMP3 | |
| SCHEMBL7917889 | 0.90 | MMP12 (0.55) | MMP12MMP13FOLH1MMEMMP2 | |
| SCHEMBL7924636 | 0.89 | MMP12 (0.65) | MMP12MMP13FOLH1MMEMMP2 | |
| SCHEMBL7928937 | 0.89 | MMP12 (0.54) | MMP12MMP13FOLH1MMP2MMP3 | |
| SCHEMBL7922593 | 0.88 | MMP12 (0.56) | MMP12MMP13FOLH1MMEMMP2 | |
| SCHEMBL3467248 | 0.87 | MMP13 (0.51) | MMP12MMP13MMP2MMP3ADAMTS4 | |
| SCHEMBL3467017 | 0.87 | MMP12 (0.57) | MMP12MMP13FOLH1MMEMMP2 | |
| SCHEMBL1861903 | 0.83 | GRIK1 (0.59) | MMP12MMP13MMEMMP2MMP3 | |
| SCHEMBL3467200 | 0.83 | MMP12 (0.60) | MMP12MMP13FOLH1MMEMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |