Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 3/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.49 |
| ▸ | TTK | P33981 | 2/20 | 0.47 |
| ▸ | BRAF | P15056 | 2/20 | 0.47 |
| ▸ | KIT | P10721 | 3/20 | 0.46 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | BCR | P11274 | 2/20 | 0.46 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 6/20 | 0.46 |
| ▸ | FYN | P06241 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469410 | 0.90 | RAD52 (0.62) | RAD52PAX8BRAFFYN | |
| SCHEMBL3467002 | 0.88 | LMNA (0.54) | RAD52PAX8TTKBRAFKIT | |
| SCHEMBL3465798 | 0.86 | BRAF (0.51) | TTKBRAFKITDDR1ABL1 | |
| SCHEMBL3466290 | 0.84 | KIT (0.46) | RAD52PAX8TTKBRAFKIT | |
| SCHEMBL3469724 | 0.82 | FYN (0.51) | RAD52TTKABL1BCRFYN | |
| SCHEMBL3469526 | 0.82 | TTK (0.48) | TTKBRAFFYN | |
| SCHEMBL3465843 | 0.82 | LMNA (0.43) | TTKBRAFKITDDR1ABL1 | |
| SCHEMBL3466303 | 0.81 | GAA (0.53) | TTKBRAFKITDDR1ABL1 | |
| SCHEMBL3469213 | 0.81 | FYN (0.55) | RAD52PAX8TTKBRAFKIT | |
| SCHEMBL13343330 | 0.81 | RAD52 (0.51) | RAD52PAX8TTKBRAFKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |