SCHEMBL346699

SCHEMBL346699

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nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.70
HMGCR P04035 1/20 0.48
CHRM1 P11229 1/20 0.48
TBXA2R P21731 1/20 0.48
ADRA1A P35348 1/20 0.48
TSHR P16473 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2C19 P33261 1/20 0.46
HIF1A Q16665 1/20 0.46
KDM4E B2RXH2 2/20 0.43
LMNA P02545 2/20 0.43
MAPT P10636 1/20 0.43
ALOX15 P16050 1/20 0.43
SLC13A5 Q86YT5 4/20 0.42
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
KMT2A Q03164 1/20 0.41
ACLY P53396 3/20 0.39
FFAR3 O14843 1/20 0.38
CPT2 P23786 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL290502 1.00 ALDH1A1 (0.70) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL23607610 0.97 ALDH1A1 (0.67) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL31078055 0.97 ALDH1A1 (0.67) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL31272367 0.86 ALDH1A1 (0.83) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL437150 0.84 ALDH1A1 (0.79) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL31223219 0.84 ALDH1A1 (0.79) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL31223216 0.84 ALDH1A1 (0.79) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL6429247 0.84 ALDH1A1 (0.79) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL226489 0.84 ALDH1A1 (0.79) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL28846450 0.84 ALDH1A1 (0.79) ALDH1A1HMGCRCHRM1TBXA2RADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595494-B2 Biological production of multi-carbon compounds from methane BIOVERDE TECH LLC (US) 2026-04-07 US disclosed
US-20240368638-A1 Biological Production of Multi-Carbon Compounds from Methane INTREXON CORPORATION 2024-11-07 US disclosed
US-11821019-B2 Biological production of multi-carbon compounds from methane PRECIGEN, INC. (US) 2023-11-21 US disclosed
US-20210171988-A1 Biological Production of Multi-Carbon Compounds from Methane BIOVERDE TECH LLC 2021-06-10 US disclosed
US-10876137-B2 Biological production of multi-carbon compounds from methane PRECIGEN, INC. (US) 2020-12-29 US disclosed
US-20170335351-A1 BIOLOGICAL PRODUCTION OF MULTI-CARBON COMPOUNDS FROM METHANE INTREXON CORPORATION (US) 2017-11-23 US disclosed
WO-2017194696-A1 BACTERIAL CELLS WITH IMPROVED TOLERANCE TO ISOBUTYRIC ACID DANMARKS TEKNISKE UNIVERSITET (DK) 2017-11-16 WO disclosed
US-9745603-B2 Biological production of multi-carbon compounds from methane INTREXON CORPORATION (US) 2017-08-29 US disclosed
US-20170152529-A1 Biological Production of Multi-Carbon Compounds from Methane INTREXON CORPORATION (US) 2017-06-01 US disclosed
US-9399783-B2 Biological production of multi-carbon compounds from methane INTREXON CORPORATION (US) 2016-07-26 US disclosed
US-8048666-B1 Ethanol production in microorganisms JOULE UNLIMITED TECHNOLOGIES, INC. (US) 2011-11-01 US disclosed
US-20110262975-A1 ENGINEERED CO2 FIXING MICROORGANISMS PRODUCING CARBON-BASED PRODUCTS OF INTEREST c/o JOULE UNLIMITED, INC. (US) 2011-10-27 US disclosed
EP-2344652-A1 ETHANOL PRODUCTION BY MICROORGANISMS Joule Unlimited, Inc. (US) 2011-07-20 EP disclosed
US-7981647-B2 Engineered CO2 fixing microorganisms producing carbon-based products of interest JOULE UNLIMITED, INC. (US) 2011-07-19 US disclosed
US-7968321-B1 Ethanol production by microorganisms JOULE UNLIMITED, INC. (US) 2011-06-28 US disclosed
US-20110151531-A1 ETHANOL PRODUCTION BY MICROORGANISMS JOULE UNLIMITED, INC. (US) 2011-06-23 US disclosed
EP-2285948-A1 ENGINEERED CO2 FIXING MICROORGANISMS PRODUCING CARBON-BASED PRODUCTS OF INTEREST Joule Unlimited, Inc. (US) 2011-02-23 EP disclosed
US-20110008861-A1 Engineered CO2 Fixing Microorganisms Producing Carbon-Based Products of Interest JOULE UNLIMITED, INC. (US) 2011-01-13 US disclosed
WO-2010044960-A1 ETHANOL PRODUCTION BY MICROORGANISMS JOULE BIOTECHNOLOGIES, INC. (US) 2010-04-22 WO disclosed
WO-2009111513-A1 ENGINEERED CO2 FIXING MICROORGANISMS PRODUCING CARBON-BASED PRODUCTS OF INTEREST JOULE BIOTECHNOLOGIES, INC. (US) 2009-09-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595494-B2 Biological production of multi-carbon compounds from methane MLYCD, ADH1C, DERA ALDH1A1 257/4885HMGCR 526/4885CHRM1 3123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.