Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.51 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442618 | 0.91 | LMNA (0.42) | ZDHHC20ZDHHC2THRATHRBLMNA | |
| SCHEMBL440561 | 0.91 | LMNA (0.42) | ZDHHC20ZDHHC2THRATHRBLMNA | |
| SCHEMBL443990 | 0.91 | LMNA (0.42) | ZDHHC20ZDHHC2THRATHRBLMNA | |
| SCHEMBL6117766 | 0.91 | LMNA (0.42) | ZDHHC20ZDHHC2THRATHRBLMNA | |
| SCHEMBL440272 | 0.90 | LMNA (0.41) | ZDHHC20ZDHHC2THRATHRBLMNA | |
| SCHEMBL6118081 | 0.89 | ZDHHC20 (0.62) | ZDHHC20ZDHHC2THRATHRBLMNA | |
| SCHEMBL442232 | 0.86 | LMNA (0.37) | ZDHHC20ZDHHC2THRATHRBLMNA | |
| SCHEMBL2333570 | 0.85 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2THRATHRBLMNA | |
| Bromide SCHEMBL28552418 | 0.81 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2THRATHRBLMNA | |
| SCHEMBL10591456 | 0.80 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2THRATHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069514-A1 | RELATIVE PERMEABILITY MODIFIERS BASED ON HYDROPHOBICALLY MODIFIED CATIONIC COPOLYMERS | ENI S.P.A. (IT) | 2010-06-24 | — | — | WO | disclosed |