SCHEMBL442232

SCHEMBL442232

C=C(C)C(=O)NCC(CCC)CCCCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
ZDHHC20 Q5W0Z9 2/20 0.37
ZDHHC2 Q9UIJ5 2/20 0.37
LCK P06239 1/20 0.37
PPARD Q03181 1/20 0.37
TSHR P16473 4/20 0.35
HTT P42858 2/20 0.35
POLB P06746 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GPR84 Q9NQS5 3/20 0.34
FFAR1 O14842 1/20 0.34
CA1 P00915 1/20 0.34
ZDHHC7 Q9NXF8 2/20 0.34
GLA P06280 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
DPP7 Q9UHL4 1/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL443990 0.95 LMNA (0.42) LMNAZDHHC20ZDHHC2LCKPPARD
SCHEMBL440561 0.95 LMNA (0.42) LMNAZDHHC20ZDHHC2LCKPPARD
SCHEMBL442618 0.95 LMNA (0.42) LMNAZDHHC20ZDHHC2LCKPPARD
SCHEMBL6117766 0.95 LMNA (0.42) LMNAZDHHC20ZDHHC2LCKPPARD
SCHEMBL440272 0.93 LMNA (0.41) LMNAZDHHC20ZDHHC2LCKPPARD
SCHEMBL3466992 0.86 ZDHHC20 (0.51) LMNAZDHHC20ZDHHC2LCKPPARD
SCHEMBL225597 0.85 TSHR (0.50) LMNATSHRHTTPOLBMAPK1
SCHEMBL14977291 0.82 ZDHHC7 (0.43) LMNAZDHHC20ZDHHC2LCKPPARD
SCHEMBL15238204 0.80 EPHX1 (0.50) LMNAZDHHC20ZDHHC2LCKPPARD
SCHEMBL439287 0.80 ACE2 (0.46) ZDHHC20ZDHHC2LCKPPARDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180333345-A1 NON-AQUEOUS COMPOSITIONS OF POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL MOIETY AND LACTAM MOIETY AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-11-22 US claimed
EP-3377547-A1 ON-AQUEOUS COMPOSITIONS OF POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL MOIETY AND LACTAM MOIETY AND APPLICATIONS THEREOF ISP Investments LLC (US) 2018-09-26 EP claimed
US-10632059-B2 Non-aqueous compositions of polymers derived from monomers having acryloyl moiety and lactam moiety and applications thereof ISP INVESTMENTS LLC (US) 2020-04-28 US disclosed
US-20180333345-A1 NON-AQUEOUS COMPOSITIONS OF POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL MOIETY AND LACTAM MOIETY AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-11-22 US disclosed
EP-3377547-A1 ON-AQUEOUS COMPOSITIONS OF POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL MOIETY AND LACTAM MOIETY AND APPLICATIONS THEREOF ISP Investments LLC (US) 2018-09-26 EP disclosed
US-8835368-B2 Compounds and a method of lubricating an internal combustion engine THE LUBRIZOL CORPORATION (US) 2014-09-16 US disclosed
EP-1669374-B1 Method for forming aqueous secondary dispersions of water insoluble polymers BASF SE (DE) 2012-11-21 EP disclosed
US-20120065110-A1 Compounds and a Method of Lubricating an Internal Combustion Engine THE LUBRIZOL CORPORATION (US) 2012-03-15 US disclosed
US-8003738-B2 Method of producing aqueous secondary dispersions of water-insoluble polymers BASF SE (DE) 2011-08-23 US disclosed
CN-1789299-A Method of producing aqueous secondary dispersions of water-insoluble polymers BASF AG (DE) 2006-06-21 CN disclosed
EP-1669374-A1 Method for forming aqueous secondary dispersions of water insoluble polymers BASF AKTIENGESELLSCHAFT (DE) 2006-06-14 EP disclosed
US-20060122321-A1 Method of producing aqueous secondary dispersions of water-insoluble polymers BASF AKTIENGESELLSCHAFT (DE) 2006-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10632059-B2 Non-aqueous compositions of polymers derived from monomers having acryloyl moiety and lactam moiety and applications thereof C9, PARG, C5 LMNA 154/4885ZDHHC20 1306/4885ZDHHC2 3290/4885
US-20180333345-A1 NON-AQUEOUS COMPOSITIONS OF POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL MOIETY AND LACTAM MOIETY AND APPLICATIONS THEREOF C9, C5, C1S LMNA 165/4885ZDHHC20 1566/4885ZDHHC2 3377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.