Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | HTT | P42858 | 5/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | ABL1 | P00519 | 5/20 | 0.62 |
| ▸ | SRC | P12931 | 5/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.55 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467177 | 0.84 | RAB9A (0.64) | MEN1KMT2ALMNAMAPTGAA | |
| SCHEMBL3467864 | 0.82 | MEN1 (0.59) | MEN1KMT2ALMNAMAPTGAA | |
| SCHEMBL3466712 | 0.82 | MEN1 (0.67) | MEN1KMT2ALMNAMAPTGAA | |
| SCHEMBL7476339 | 0.77 | MAPT (0.67) | MEN1KMT2ALMNAMAPTGAA | |
| SCHEMBL8565680 | 0.77 | MAPT (0.60) | MEN1KMT2ALMNAMAPTGAA | |
| SCHEMBL16971035 | 0.76 | ABL1 (1.00) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL8561964 | 0.74 | HTT (0.75) | MEN1KMT2ALMNAMAPTGAA | |
| SCHEMBL8559872 | 0.73 | HTT (0.73) | MEN1KMT2ALMNAMAPTGAA | |
| SCHEMBL7481013 | 0.73 | MAPT (0.63) | MEN1KMT2ALMNAMAPTGAA | |
| SCHEMBL7480423 | 0.73 | MAPT (0.66) | MEN1KMT2ALMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |