Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916834 | 0.85 | MAOB (0.52) | SLC13A5MMP3 | |
| SCHEMBL3467260 | 0.83 | MMP2 (0.60) | SLC13A5MMEMMP2MMP3HDAC1 | |
| SCHEMBL1861903 | 0.82 | GRIK1 (0.59) | MMEMMP2MMP3FFAR1HDAC2 | |
| SCHEMBL7918296 | 0.82 | MMP2 (0.56) | MMEMMP2MMP3GRIK1 | |
| SCHEMBL3468867 | 0.80 | GRIA2 (0.51) | MMEMMP2MMP3FFAR1FFAR4 | |
| SCHEMBL3467381 | 0.80 | SLC7A5 (0.50) | MMP2MMP3GRIK1 | |
| SCHEMBL3467455 | 0.79 | FDFT1 (0.56) | MMEMMP2MMP3GRIK1 | |
| SCHEMBL3467287 | 0.77 | FOLH1 (0.52) | MMEMMP2MMP3GRIK1 | |
| SCHEMBL7929474 | 0.77 | GRIK1 (0.46) | MMEMMP2MMP3GRIK1 | |
| SCHEMBL7924101 | 0.77 | GRIK1 (0.54) | MMEMMP2MMP3GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | claimed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |