Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.46 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924101 | 0.88 | GRIK1 (0.54) | MMP2MMP3GRIK1MMEFDFT1 | |
| SCHEMBL1861903 | 0.88 | GRIK1 (0.59) | MMP2MMP3GRIK1MMEFDFT1 | |
| SCHEMBL3466739 | 0.87 | MMP2 (0.52) | MMP2MMP3TAAR1HCAR2SRC | |
| SCHEMBL3468867 | 0.86 | GRIA2 (0.51) | MMP2MMP3HCAR2GRIK1MME | |
| SCHEMBL3467260 | 0.84 | MMP2 (0.60) | MMP2MMP3GRIK1MMEGPR34 | |
| SCHEMBL7929474 | 0.83 | GRIK1 (0.46) | MMP2MMP3GRIK1MMEFDFT1 | |
| SCHEMBL3467287 | 0.83 | FOLH1 (0.52) | MMP2MMP3GRIK1MMEFDFT1 | |
| SCHEMBL7932591 | 0.82 | MMP12 (0.63) | MMP2MMP3GRIK1MMEFDFT1 | |
| SCHEMBL7916834 | 0.82 | MAOB (0.52) | MMP3HCAR2 | |
| SCHEMBL3467418 | 0.82 | SLC13A5 (0.55) | MMP2MMP3GRIK1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |