Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 5/20 | 0.45 |
| ▸ | MMP3 | P08254 | 5/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467101 | 0.89 | FOLH1 (0.46) | MMEMMP12MMP13 | |
| SCHEMBL3467287 | 0.88 | FOLH1 (0.52) | GRIK1MMP2MMP3MMP1MMP9 | |
| SCHEMBL1861903 | 0.86 | GRIK1 (0.59) | GRIK1MMP2MMP3MMP1MMP9 | |
| SCHEMBL3467381 | 0.85 | SLC7A5 (0.50) | GRIK1MMP2MMP3MMP1MMP9 | |
| SCHEMBL3466490 | 0.85 | CYP17A1 (0.52) | MMP2MMP3MME | |
| SCHEMBL3468867 | 0.84 | GRIA2 (0.51) | GRIK1MMP2MMP3MMP9MME | |
| SCHEMBL7918296 | 0.83 | MMP2 (0.56) | GRIK1MMP2MMP3MMEFDFT1 | |
| SCHEMBL7916834 | 0.82 | MAOB (0.52) | MMP3MMP12 | |
| SCHEMBL7917882 | 0.82 | DRD4 (0.53) | — | |
| SCHEMBL7932591 | 0.80 | MMP12 (0.63) | GRIK1MMP2MMP3MMEMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |