Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | GLS | O94925 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467586 | 0.81 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL3467295 | 0.80 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL3467474 | 0.79 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL3467957 | 0.75 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL15727672 | 0.72 | GLS (0.77) | ALDH1A1GLSTDP1 | |
| SCHEMBL3466719 | 0.72 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL9796280 | 0.71 | CA2 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL14987347 | 0.68 | GLS (1.00) | GLSLMNAMAPT | |
| SCHEMBL3466980 | 0.68 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL21443424 | 0.68 | GLS (0.69) | ALDH1A1GLSTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |