Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 9/20 | 0.40 |
| ▸ | CCR3 | P51677 | 9/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2796876 | 0.76 | EPHX2 (0.46) | SMN1; SMN2EPHX2 | |
| SCHEMBL3467746 | 0.75 | HRH3 (0.39) | HRH1CCR3KCNH2SMN1; SMN2GAA | |
| SCHEMBL2794617 | 0.68 | DRD4 (0.51) | HRH1CCR3KCNH2SMN1; SMN2 | |
| SCHEMBL2799432 | 0.67 | SIGMAR1 (0.49) | HRH1CCR3HRH3KDM4E | |
| SCHEMBL1010704 | 0.67 | SCD (0.51) | HRH1CCR3 | |
| Hydrochloric Acid SCHEMBL1010471 | 0.66 | SCD (0.50) | HRH1CCR3 | |
| SCHEMBL14423906 | 0.65 | HRH3 (0.66) | HRH3 | |
| SCHEMBL7506349 | 0.64 | HRH3 (0.42) | SMN1; SMN2HRH3 | |
| SCHEMBL27675181 | 0.64 | GAA (0.62) | GAA | |
| SCHEMBL6992881 | 0.64 | LIPG (0.41) | HRH1CCR3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077915-A1 | NOVEL COMPOUNDS USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-07-08 | — | — | WO | disclosed |