Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKLR | P30613 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468222 | 0.82 | KMT2A (0.35) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL3469175 | 0.80 | GAA (0.56) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL3478684 | 0.77 | MAPK1 (0.52) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL13196446 | 0.76 | GAA (0.48) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL2780829 | 0.75 | GAA (0.59) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL3469163 | 0.74 | CASP3 (0.55) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL3478621 | 0.73 | CNR2 (0.48) | KMT2APOLBMEN1CNR2ALDH1A1 | |
| SCHEMBL3468221 | 0.73 | CNR2 (0.68) | POLBCNR2ALDH1A1 | |
| SCHEMBL13196452 | 0.73 | GAA (0.50) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL5332060 | 0.73 | ALDH1A1 (0.58) | GAAMAPK1KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077839-A1 | SUBSTITUTED OXINDOL CB2 AGONISTS FOR PAIN TREATMENT | WYETH LLC (FORMERLY KNOWN AS WYETH) (US) | 2010-07-08 | — | — | WO | disclosed |