Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3478684 | 0.83 | MAPK1 (0.52) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL2780829 | 0.83 | GAA (0.59) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL3469163 | 0.82 | CASP3 (0.55) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL13196452 | 0.81 | GAA (0.50) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL3467565 | 0.80 | GAA (0.47) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL13196418 | 0.80 | GAA (0.62) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL3467433 | 0.79 | KMT2A (0.49) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL13196446 | 0.79 | GAA (0.48) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL2825338 | 0.79 | MAPK1 (0.54) | GAAMAPK1KMT2APOLBMEN1 | |
| SCHEMBL2781263 | 0.78 | GAA (0.53) | GAAMAPK1KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077839-A1 | SUBSTITUTED OXINDOL CB2 AGONISTS FOR PAIN TREATMENT | WYETH LLC (FORMERLY KNOWN AS WYETH) (US) | 2010-07-08 | — | — | WO | claimed |