Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | YES1 | P07947 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332060 | 0.84 | ALDH1A1 (0.58) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL3469175 | 0.83 | GAA (0.56) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL2780829 | 0.80 | GAA (0.59) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL3469163 | 0.79 | CASP3 (0.55) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL13196446 | 0.78 | GAA (0.48) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL13196452 | 0.78 | GAA (0.50) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL3467565 | 0.77 | GAA (0.47) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL5335747 | 0.76 | GAA (0.62) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL2825338 | 0.76 | MAPK1 (0.54) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL3467433 | 0.76 | KMT2A (0.49) | MAPK1GAAKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077839-A1 | SUBSTITUTED OXINDOL CB2 AGONISTS FOR PAIN TREATMENT | WYETH LLC (FORMERLY KNOWN AS WYETH) (US) | 2010-07-08 | — | — | WO | disclosed |