Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11101389 | 0.78 | PTGES2 (0.50) | KDRMEN1KMT2ACASP6GFER | |
| SCHEMBL3335279 | 0.74 | FGFR3 (0.47) | FGFR3KDRCTSVCTSLCTSS | |
| SCHEMBL30437048 | 0.73 | PTGES2 (0.58) | KDRMEN1KMT2ACASP6GFER | |
| SCHEMBL148204 | 0.72 | CA2 (0.54) | MEN1KMT2ACASP6GFERCA1 | |
| SCHEMBL11101419 | 0.70 | TSHR (0.52) | KDRMEN1KMT2ACASP6GFER | |
| SCHEMBL11514694 | 0.70 | CTSV (0.41) | FGFR3KDRCTSVCTSLCTSS | |
| SCHEMBL25488567 | 0.68 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL31301193 | 0.68 | KDM4E (0.53) | MEN1KMT2AALDH1A1 | |
| SCHEMBL31264268 | 0.68 | NOTUM (0.46) | KMT2ABRD4 | |
| SCHEMBL1174898 | 0.68 | TRIM24 (0.41) | FGFR3KDRCTSVCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |